Granted Patent
B2
US 12,419,747 · App. 18/343,337 · Granted Sep 23, 2025
Device, system, and method for transcatheter treatment of valvular regurgitation
Inventors:
Alexander K. Khairkhahan (Palo Alto, CA); Janine C. Robinson (Half Moon Bay, CA); Alan R. Klenk (San Jose, CA); Anuja Patel (Palo Alto, CA); Zaya Tun (Livermore, CA); Robert Quintos (Palo Alto, CA); Brett Snyder (Campbell, CA)
Assignee:
Polares Medical Inc.
A61F2/246A61F2/2466A61F2210/0014A61F2220/0016A61F2220/0075A61F2230/0006A61F2230/0091A61F2250/0018A61F2250/0098
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Abstract
The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance element for implantation across the valve; a system including the coaptation assistance element and anchors for implantation; a system including the coaptation assistance element and delivery catheter; and a method for transcatheter implantation of a coaptation element across a heart valve.
Claims (32)
1. A coaptation assistance element for treating mal-coaptation of a heart valve, the heart valve having an annulus, the coaptation assistance element comprising:
a first surface and an opposed second surface, each surface bounded by a first lateral edge, a second lateral edge, an inferior edge, and a superior edge;
a hub; and
a plurality of struts spaced around the hub and extending outward from the hub, the plurality of struts comprising at least a first strut configured to be implanted within a heart and a second strut configured to be implanted within the heart,
wherein the coaptation assistance element comprises lamination configured to surround one or more struts of the plurality of struts.
2. The coaptation assistance element of claim 1 , wherein the coaptation assistance element is configured to provide an atraumatic surface to reduce the risk of native leaflet damage.
3. The coaptation assistance element of claim 1 , wherein the lamination comprises ePTFE.
4. The coaptation assistance element of claim 1 , wherein the first surface comprises ePTFE.
5. The coaptation assistance element of claim 1 , wherein the second surface comprises ePTFE.
6. A coaptation assistance element for treating mal-coaptation of a heart valve, the heart valve having an annulus, the coaptation assistance element comprising:
a first surface and an opposed second surface, each surface bounded by a first lateral edge, a second lateral edge, an inferior edge, and a superior edge, wherein the first surface comprises a first coaptation surface configured for an anterior leaflet to coapt against;
a hub;
a plurality of struts spaced around the hub and extending outward from the hub, the plurality of struts comprising at least a first strut configured to be implanted within a heart and a second strut configured to be implanted within the heart,
wherein the coaptation assistance element comprises a reinforced edge with increased thickness.
7. The coaptation assistance element of claim 6 , wherein the reinforced edge is configured to reduce trauma to native tissue.
8. The coaptation assistance element of claim 6 , wherein the reinforced edge is configured to reduce contact between the coaptation assistance element and a posterior leaflet.
9. The coaptation assistance element of claim 6 , wherein the first surface comprises the reinforced edge.
10. The coaptation assistance element of claim 6 , wherein the second surface comprises the reinforced edge.
11. The coaptation assistance element of claim 6 , wherein the first lateral edge comprises the reinforced edge.
12. The coaptation assistance element of claim 6 , wherein the inferior edge comprises the reinforced edge.
13. The coaptation assistance element of claim 6 , wherein the reinforced edge is at least partially circumferential.
14. A coaptation assistance element for treating mal-coaptation of a heart valve, the heart valve having an annulus, the coaptation assistance element comprising:
a first surface and an opposed second surface, each surface bounded by a first lateral edge, a second lateral edge, an inferior edge, and a superior edge, wherein the first surface comprises a first coaptation surface configured for the anterior leaflet to coapt against;
a hub;
a plurality of struts spaced around the hub and extending outward from the hub,
wherein the coaptation assistance element comprises a layer of pericardium.
15. The coaptation assistance element of claim 14 , wherein the plurality of struts comprise nitinol.
16. The coaptation assistance element of claim 14 , wherein the hub and the plurality of struts are integrally formed.
17. The coaptation assistance element of claim 14 , wherein the coaptation assistance element comprises the same material on the first surface and the second surface.
18. The coaptation assistance element of claim 14 , wherein the coaptation assistance element comprises different materials on the first surface, or a portion thereof, and the second surface, or a portion thereof.
19. The coaptation assistance element of claim 14 , wherein the layer of pericardium comprises porcine pericardium.
20. The coaptation assistance element of claim 14 , wherein the layer of pericardium comprises bovine pericardium.
Assignments (2)
CHANGE OF NAME
Recorded Feb 21, 2024
From: MIDDLE PEAK MEDICAL INC.
To: POLARES MEDICAL INC.
Reel/Frame 066644/0446 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Sep 11, 2023
From: KHAIRKHAHAN, ALEXANDER K.; ROBINSON, JANINE C.; KLENK, ALAN R.; PATEL, ANUJA; TUN, ZAYA; QUINTOS, ROBERT; SNYDER, BRETT
To: MIDDLE PEAK MEDICAL, INC.
Reel/Frame 064865/0628 →
Continuity (5)
Provisional Application
62470684
· Mar 13, 2017
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