IP Library › Granted Patent US 12,285,602
Granted Patent B2
US 12,285,602 · App. 18/377,968 · Granted Apr 29, 2025

Methods of treating disease using auricular peripheral nerve field stimulation

Inventors: Christopher R. Brown (Greensburg, IN); Gary M. Peterson (Versailles, IN)
Assignee: NEURAXIS, INC.
A61N1/0529A61N1/0551A61N1/36071A61N1/36096A61K31/485
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Quick Facts
Patent No.
US 12,285,602
App. No.
18/377,968
Granted
Apr 29, 2025
Kind
B2
Abstract

A method for treating pain or discomfort in a patient is disclosed. The method comprises stimulating a cranial nerve with an electrical signal. The pain or discomfort may be a withdrawal symptom. The cranial nerve may be in an auricular area of the patient. The cranial nerve may be cranial nerve V, cranial nerve VII, cranial nerve IX, cranial nerve X, or branches of greater and lesser occipital nerves thereof and their associated neurovascular bundles. The withdrawal symptom may result from cessation of an opioid. The method may further comprise administering a secondary drug treats one or more of the withdrawal symptoms and addiction. The secondary drug may be administered about one day to about one week after initiating the stimulating step.

Claims (14)

1. A method of treating anxiety comprising:

altering response characteristics of amygdala neurons and lumbar neurons, wherein the altering step includes:

stimulating a cranial nerve with an electrical signal.

2. The method of claim 1 , wherein the cranial nerve is selected from the group consisting of cranial nerve V, cranial nerve VII, cranial nerve IX, cranial nerve X, and branches of greater and lesser occipital nerves thereof and their associated neurovascular bundles.

3. The method of claim 2 , wherein the cranial nerve is cranial nerve V.

4. The method of claim 2 , wherein the cranial nerve is cranial nerve V and associated neurovascular bundles.

5. The method of claim 2 , wherein the cranial nerve is cranial nerve VII.

6. The method of claim 2 , wherein the cranial nerve is cranial nerve VII and associated neurovascular bundles.

7. The method of claim 2 , wherein the cranial nerve is cranial nerve IX.

8. The method of claim 2 , wherein the cranial nerve is cranial nerve IX and associated neurovascular bundles.

9. The method of claim 2 , wherein the cranial nerve is cranial nerve X.

10. The method of claim 2 , wherein the cranial nerve is cranial nerve X and associated neurovascular bundles.

11. The method of claim 2 , wherein the cranial nerve is branches of greater and lesser occipital nerves.

12. The method of claim 2 , wherein the cranial nerve is branches of greater and lesser occipital nerves and associated neurovascular bundles.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 1, 2024
From: BROWN, CHRISTOPHER R.; PETERSON, GARY M.
To: INNOVATIVE HEALTH SOLUTIONS, INC.
Reel/Frame 069106/0481 →
CHANGE OF NAME Recorded Nov 1, 2024
From: INNOVATIVE HEALTH SOLUTIONS, INC.
To: NEURAXIS, INC.
Reel/Frame 069291/0066 →
Continuity (6)
Continuation 17725761 · Apr 21, 2022
Continuation 16534159 · Aug 7, 2019
Continuation 15488416 · Apr 14, 2017
Provisional Application 62324598 · Apr 19, 2016
Provisional Application 62323369 · Apr 15, 2016
Related Publication 20240033505A1 · Feb 1, 2024
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