IP Library › Granted Patent US 12,220,870
Granted Patent B2
US 12,220,870 · App. 18/519,764 · Granted Feb 11, 2025

Continuous digital light processing additive manufacturing of implants

Inventors: H. David Dean (Shaker Heights, OH); Al Siblani (Dearborn Heights, MI); Eric J. Mott (Plainwell, MI); John P. Fisher (Kensington, MD); Martha O. Wang (Columbia, MO); Antonios G. Mikos (Houston, TX)
B29C64/386A61L27/50A61L27/56A61L27/60B33Y30/00B33Y50/00B33Y70/00B33Y80/00G03F7/0047G03F7/029G03F7/105G03F7/2008B29C64/135G02B26/0833
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Quick Facts
Patent No.
US 12,220,870
App. No.
18/519,764
Granted
Feb 11, 2025
Kind
B2
Abstract

A light polymerizable composition for use in the additive manufacturing of medical devices may include a first photo-initiator and a second photo-initiator. The first photo-initiator activates to initiate curing of the composition when exposed to light of a first wavelength in an additive manufacturing device and the second photo-initiator limits the transmission of the light of the first wavelength that activates the first photo-initiator in the additive manufacturing device. The second photo-initiator is activated to further cure the composition when exposed to a light of a second wavelength different from the first wavelength by activating the second photo-initiator to produce free radicals at a higher rate when exposed to the light of the second wavelength than when exposed to the light of the first wavelength.

Claims (17)

1. A light polymerizable composition for use in the additive manufacturing of medical devices, comprising:

a first photo-initiator and a second photo-initiator, wherein the first photo-initiator activates to initiate curing of the composition when exposed to light of a first wavelength in an additive manufacturing device and the second photo-initiator limits the transmission of the light of the first wavelength that activates the first photo-initiator in the additive manufacturing device, and wherein the second photo-initiator is activated to further cure the composition when exposed to a light of a second wavelength different from the first wavelength by activating the second photo-initiator to produce free radicals at a higher rate when exposed to the light of the second wavelength than when exposed to the light of the first wavelength.

2. The light polymerizable composition of claim 1 wherein one or both of the first and second photo-initiators are an acylphosphine oxide.

3. The light polymerizable composition of claim 2 wherein the first photo-initiator is Bis(2,4,6-trimethylbenzoyl)-phenylphosphineoxide (BAPO).

4. The light polymerizable composition of claim 2 wherein the second photo-initiator is Bis(.eta.5-2,4-cylcopentadien-1-yl)-bis(2,6-difluoro-3-(1H-pyrrol-1-yl)-phenyl) titanium.

5. The light polymerizable composition of claim 2 wherein the amount of the first photo-initiator and the second photo-initiator are about 0.1 to 5.0% by weight of polymer and solvent.

6. The light polymerizable composition of claim 5 wherein the amount of Bis(.eta.5-2,4-cylcopentadien-1-yl)-bis(2,6-difluoro-3-(1H-pyrrol-1-yl)-phenyl) titanium by weight of polymer and solvent is about 0.1 to 5.0%.

7. The light polymerizable composition of claim 6 wherein the amount of BAPO by weight of the polymer and solvent is about 0.1 to 5.0%.

8. A light polymerizable composition for use in the additive manufacturing of medical devices, comprising:

a first photo-initiator that activates to initiate curing of the composition when exposed to light of a first wavelength in an additive manufacturing device; and

a second photo-initiator that changes color of the composition to limit the transmission of the light of the first wavelength that activates the first photo-initiator in the additive manufacturing device, the second photo-initiator activates to produce free radicals at a higher rate when exposed to light of a second wavelength different from the first wavelength than when exposed to the light of the first wavelength to further cure the composition when exposed to the light of the second wavelength.

9. The light polymerizable composition of claim 8 wherein one or both of the first and second photo-initiators are an acylphosphine oxide.

10. The light polymerizable composition of claim 9 wherein the first photo-initiator is Bis(2,4,6-trimethylbenzoyl)-phenylphosphineoxide (BAPO).

11. The light polymerizable composition of claim 9 wherein the second photo-initiator is Bis(.eta.5-2,4-cylcopentadien-1-yl)-bis(2,6-difluoro-3-(1H-pyrrol-1-yl)-phenyl) titanium.

12. The light polymerizable composition of claim 11 wherein the amount of Bis(.eta.5-2,4-cylcopentadien-1-yl)-bis(2,6-difluoro-3-(1H-pyrrol-1-yl)-phenyl) titanium by weight of polymer and solvent is about 0.1 to 5.0%.

13. The light polymerizable composition of claim 9 wherein the amount of the first photo-initiator and the second photo-initiator are about 0.1 to 5.0% by weight of polymer and solvent.

14. The light polymerizable composition of claim 13 wherein the amount of BAPO by weight of the polymer and solvent is about 0.1 to 5.0%.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 21, 2026
From: FISHER, JOHN; KIM, KYOBUM; WANG, MARTHA
To: UNIVERSITY OF MARYLAND, COLLEGE PARK
Reel/Frame 073539/0022 →
Continuity (7)
Continuation 15634792 · Jun 27, 2017
Continuation In Part 14648446
Continuation In Part 13817612
Provisional Application 61731843 · Nov 30, 2012
Provisional Application 61491194 · May 29, 2011
Provisional Application 61375353 · Aug 20, 2010
Related Publication 20240100777A1 · Mar 28, 2024
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