IP Library Granted Patent US 12,429,539
Granted Patent B2
US 12,429,539 · App. 18/543,775 · Granted Sep 30, 2025

Systems and methods for volumetric acquisition in a single-sided MRI scanner

Inventor: Muller Francis De Matos Gomes (Hayward, CA)
Assignee: Promaxo, Inc.
G01R33/3808G01R33/3415G01R33/381G01R33/383G01R33/385G01R33/4616G01R33/4835A61B5/4381
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Quick Facts
Patent No.
US 12,429,539
App. No.
18/543,775
Granted
Sep 30, 2025
Kind
B2
Abstract

A method for performing magnetic resonance imaging is provided. The method includes providing a magnetic resonance imaging system comprising: a radio frequency receive system comprising a radio frequency receive coil, and a housing, wherein the housing comprises a permanent magnet for providing an inhomogeneous permanent gradient field, a radio frequency transmit system, and a single-sided gradient coil set. The method also includes placing the receive coil proximate a target subject; applying a sequence of chirped pulses via the transmit system; applying a multi-slice excitation along the inhomogeneous permanent gradient field; applying a plurality of gradient pulses via the gradient coil set orthogonal to the inhomogeneous permanent gradient field; acquiring a signal of the target subject via the receive system, wherein the signal comprises at least two chirped pulses; and forming a magnetic resonance image of the target subject.

Claims (27)

1. A method for performing magnetic resonance imaging comprising:

projecting an inhomogeneous permanent gradient magnetic field to a target subject via a single-sided gradient coil set, wherein the gradient coil set is non-planar and oriented to partially surround the target subject;

placing a receive coil proximate the target subject;

applying a sequence of chirped pulses having a wide bandwidth;

selecting a slice selection gradient having the same wide bandwidth;

applying a multi-slice excitation technique along an axis of the inhomogeneous permanent gradient magnetic field;

applying a plurality of gradient pulses orthogonal to the inhomogeneous permanent gradient magnetic field;

acquiring a signal of the target subject via the receive coil; and

forming a magnetic resonance image of the target subject.

2. The method of claim 1 , wherein application of the sequence of chirped pulses, multi-slice excitation technique, and gradient pulses are each timed to refocus a magnetization of the inhomogeneous permanent gradient magnetic field at a time of acquisition of the signal.

3. The method of claim 2 , wherein each magnetization focuses in a region of interest, wherein the region of interest encompasses the target subject.

4. The method of claim 3 , wherein the region of interest has a diameter of 4 to 12 inches.

5. The method of claim 3 , wherein the imaging system further comprises a tuning box and a radio frequency transmit coil, wherein the tuning box is configured to alter frequency response of the transmit coil.

6. The method of claim 5 , wherein the transmit coil is non-planar and oriented to partially surround the region of interest.

7. The method of claim 3 , wherein the receive coil is a flexible coil configured to be affixed to an anatomical portion of a patient for imaging within the region of interest.

8. The method of claim 3 , wherein the receive coil is in one of a single-loop coil configuration, figure-8 coil configuration, or butterfly coil configuration, wherein the receive coil is smaller than the region of interest.

9. The method of claim 1 , wherein the sequence of chirped pulses comprise identical bandwidths and differing durations.

10. The method of claim 9 , wherein the sequence of chirped pulses have a bandwidth ranging from 1 kHz to 10 kHz, 10 kHz to 40 kHz, 40 kHz to 100 kHz, 100 kHz to 400 kHz, 400 kHz to 1 MHz, or any ranges of bandwidth thereof.

11. The method of claim 1 , wherein the sequence of chirped pulses are configured to produce a 1-dimensional signal along an axis of the permanent gradient field.

12. The method of claim 11 , wherein the 1-dimensional signal is a first 1-dimensional signal, and wherein the gradient pulses are configured to produce a second 1-dimensional signal and a third 1-dimensional signal that are orthogonal to each other and to the axis of the permanent gradient field.

13. The method of claim 1 , wherein the gradient pulses are configured for encoding spatial information to the signal.

14. The method of claim 1 , wherein the combination of the permanent gradient field and the sequence of chirped pulses are configured for slice selection in the permanent gradient and a frequency encoding gradient.

15. The method of claim 1 , wherein the target subject is an anatomical portion of a body.

16. The method of claim 1 , wherein the receive coil comprises an array of receive coils and each of the array of receive coils is configured for specific anatomical portion of a body.

17. The method of claim 1 , wherein the sequence of chirped pulses induce a signal in the target subject, and the signal is received by the receive coil.

18. The method of claim 1 , wherein the magnetic resonance imaging system further comprises a signal conditioning box and a control system, wherein the signal conditioning box is configured to turn the control system on and off with a blanking signal.

19. The method of claim 18 , wherein turning the system on and off with the blanking signal respectively enables and disables a radio frequency amplifier.

Assignments (3)
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Jul 2, 2026
From: PROMAXO LLC
To: WINDWARD FAMILY OFFICE, LLC
Reel/Frame 075893/0395 →
SECURITY INTEREST Recorded Sep 17, 2025
From: PROMAXO LLC
To: EASTWARD FUND MANAGEMENT, LLC
Reel/Frame 072916/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 18, 2023
From: DE MATOS GOMES, MULLER FRANCIS
To: PROMAXO, INC.
Reel/Frame 065900/0200 →
Continuity (4)
Continuation 17938229 · Oct 5, 2022
Continuation 17438898
Provisional Application 62823511 · Mar 25, 2019
Related Publication 20240418811A1 · Dec 19, 2024
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