Granted Patent B2

US 12,318,399 · App. 18/655,974 · Granted Jun 3, 2025

Inventors: Alexandra M. Capano (Philadelphia, PA); Pradeep Singh Tanwar (Fletcher, AU)

Assignees: Ecofibre USA Inc.; The University of Newcastle

A61K31/658A61K31/282A61K31/337A61K31/353A61K31/704A61K36/185A61P35/00

Abstract

Claims (9)

1. A method of treatment of a gynecological disease or disorder comprising administering to a patient in need thereof an effective amount of a composition comprising:

a cannabis extract and a flavonoid selected from the group consisting of: a flavonoid having the following structure:

wherein attached at each of R3, R5, R6, R7, R8, R2′, R3′, R4′, R5′, and R6′ is a hydrogen or a hydroxyl;

wherein the cannabis extract is selected from the group consisting of: a broad spectrum hemp extract, a full spectrum hemp extract, a cannabidiol (CBD) isolated, and combinations thereof;

wherein the cannabis extract comprises between 50% and 100% by weight of cannabidiol; and

wherein the ratio of the cannabis extract to the flavonoid is between 5 μg/mL: 1 μM to 5 μg/mL: 200 μM.

2. The method of claim 1 wherein the flavonoid comprises at least two hydroxyl groups attached at R3, R5, R6, R7, R8, R2′, R3′, R4′, R5′, and R6′.

3. The method of claim 1 wherein the flavonoid comprises a hydroxyl group attached at R3 and a hydroxyl group attached at at least two of R5, R6, R7, R8, R2′, R3′, R4′, R5′, and R6′.

4. The method of claim 1 further comprising a chemotherapeutic agent.

Assignments (3)

Continuity (3)

References Cited (106)