IP Library Granted Patent US 12,416,643
Granted Patent B2
US 12,416,643 · App. 18/663,846 · Granted Sep 16, 2025

Systems and methods for pipette robots

Inventors: Andrew Sigler (Brooklyn, NY); Taylor Schlaff Goodman (New York, NY); Nicholas Pease Starno (Fort Pierce, FL); Jonathan Preston Badal (Brooklyn, NY)
Assignee: Opentrons Labworks Inc.
G01N35/0099B01L3/0227B01L3/0237G01N35/00693G01N35/1011
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Quick Facts
Patent No.
US 12,416,643
App. No.
18/663,846
Granted
Sep 16, 2025
Kind
B2
Abstract

Systems and methods applicable, for instance, to pipette robots. A pipette robot can perform one or more operations regarding deck calibration, one or more operations regarding pipette tip/probe calibration, one or more operations regarding pipette tip pick up, and/or one or more operations regarding tip ejection.

Claims (24)

1. A pipette robot, comprising:

a computer, wherein said computer comprises:

at least one processor; and

a memory including instructions;

a frame;

a deck operatively connected to the frame;

a gantry operatively connected to the frame;

a Z-axis motor operatively connected to the gantry, wherein the Z-axis motor is further operatively connected to the at least one processor; and

a pipette operatively connected to the gantry, wherein said pipette comprises a pipette body, and wherein the Z-axis motor is configured to travel the pipette along a Z-axis,

wherein the instructions configure the pipette robot to perform a method comprising:

aligning, using the gantry, the pipette with a pipette tip;

selecting, by the at least one processor, a current, wherein the selected current causes the Z-axis motor to, if stalled, output a stall torque that is reduced relative to a maximum stall torque of the Z-axis motor;

placing, using the at least one processor, a limit that the Z-axis motor draw no more than the selected current; and

moving, using the Z-axis motor, the pipette downwards until the pipette makes contact with the pipette tip and the Z-axis motor stalls, wherein the pipette tip becomes attached to the pipette.

2. The pipette robot of claim 1 , wherein the method further comprises:

removing, using the at least one processor, the limit that the Z-axis motor draw no more than the selected current; and

one or more of aspirating liquids using the pipette and dispensing liquids using the pipette.

3. The pipette robot of claim 1 , wherein the method further comprises:

moving, using the Z-axis motor, the pipette upwards until the pipette activates a Z-axis frame switch; and

recording, using the at least one processor, a distance between the Z-axis frame switch and a location which corresponds to said stalling of the Z-axis motor.

4. The pipette robot of claim 1 , wherein the method further comprises:

detecting said stalling of the Z-axis motor by performing one or more of:

monitoring, using the at least one processor, a current drawn by the Z-axis motor; and

monitoring, using the at least one processor, a back-electromotive force (EMF) emitted by the Z-axis motor.

Assignments (2)
SECURITY INTEREST Recorded Jul 7, 2025
From: OPENTRONS LABWORKS INC.; REOPEN DIAGNOSTICS, LLC; NEOCHROMOSOME, INC.
To: OXFORD FINANCE LLC, AS COLLATERAL AGENT
Reel/Frame 071615/0854 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 14, 2024
From: SIGLER, ANDREW, MR.; GOODMAN, TAYLOR SCHLAFF, MR.; STARNO, NICHOLAS PEASE, MR.; BADAL, JONATHAN PRESTON
To: OPENTRONS LABWORKS INC.
Reel/Frame 067409/0611 →
Continuity (4)
Division 17972295 · Oct 24, 2022
Division 16722749 · Dec 20, 2019
Provisional Application 62784135 · Dec 21, 2018
Related Publication 20240310398A1 · Sep 19, 2024
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