Granted Patent B1

US 12,575,791 · App. 18/945,087 · Granted Mar 17, 2026

Inventors: Nathan Zavanelli (Atlanta, GA); Brennan Torstrick (Atlanta, GA); Nick Bolus (Birmingham, AL); Mohsen Safaei (Smyrna, GA); Brett Klosterhoff (St. Louis, MO)

Assignee: HUXLEY MEDICAL, INC.

A61B5/6833A61B5/0205A61B5/725A61B2560/0214A61B2562/0219A61B2562/043A61B2562/166

Abstract

Claims (47)

1 . A patch device comprising:

a photoplethysmography (PPG) sensor comprising at least one light emitting diode (LED);

an adhesive layer configured to adhere to skin of a chest of an individual;

one or more rigid components connected to the adhesive layer, the one or more rigid components comprising a hardware processor for communication with the PPG sensor, the hardware processor configured to receive a plurality of measurements from each of the PPG sensor; and

an air gap between a lower surface of the adhesive layer and a lower surface of the PPG sensor for providing a compressive downward force when the adhesive layer and the PPG sensor are in contact with the skin of the chest of the individual, thereby improving signal quality of the PPG sensor, wherein:

the compressive downward force is at least 0.5 Newtons;

the PPG sensor passes through the adhesive layer;

the adhesive layer and the PPG sensor are configured to be in contact with the skin of the chest of the individual simultaneously with at least a portion of the air gap therebetween; and

the hardware processor is further configured to:

measure, via the PPG sensor, cutaneous blood flow and volume; and

determine blood oxygen saturation (SpO2) derived from the cutaneous blood flow and volume.

2 . The patch device of claim 1 , further comprising a plurality of flexible layers.

3 . The patch device of claim 2 , wherein the plurality of flexible layers comprise:

a silver layer;

a dielectric layer; and

a printed circuit board layer.

4 . The patch device of claim 1 , wherein the PPG sensor further comprises an array board comprising the at least one LED.

5 . The patch device of claim 4 , wherein the PPG sensor further comprises an adaptive filter configured to reduce a noise of readings from the array board.

6 . The patch device of claim 1 , wherein the hardware processor is further configured to:

identify an amplitude of a signal from the PPG sensor;

determine that the amplitude of the signal exceeds a predetermined threshold; and

in response to the amplitude exceeding the predetermined threshold, generate an indication that the patch device is improperly applied to the chest of the individual.

7 . The patch device of claim 6 , wherein the amplitude corresponds to at least one of a red signal or an infrared signal.

8 . The patch device of claim 1 , wherein the PPG sensor is configured to be positioned over and in contact with the chest of the individual via the adhesive layer.

9 . The patch device of claim 1 , wherein the air gap is less than or equal to 5.25 mm.

10 . The patch device of claim 1 , further comprising a plurality of sensors comprising a gyroscope, an accelerometer, a compass, wherein the hardware processor is configured to determine a plurality of cardiorespiratory parameters via chest accelerometry based on the plurality of sensors.

11 . The patch device of claim 1 , further comprising an electrocardiogram (ECG) sensor, wherein the hardware processor is further configured to determine heart rate variability based on measurements from the PPG sensor and the ECG sensor.

12 . The patch device of claim 1 , further comprising a digital signal processor circuit and a second analog to digital converter.

13 . The patch device of claim 1 , wherein the plurality of measurements describe at least one analog waveform.

14 . The patch device of claim 1 , wherein the patch device comprises a rectangular prism shape with a size of between 11 and 16 millimeters deep by between 42 and 47 millimeters long by between 32 and 37 millimeters wide.

15 . The patch device of claim 1 , wherein the air gap is at least 0.1 mm.

16 . The patch device of claim 1 , wherein the one or more rigid components are connected to a first side of the adhesive layer.

17 . The patch device of claim 1 , wherein the PPG sensor comprises a plurality of LEDs.

18 . A patch device comprising:

a photoplethysmography (PPG) sensor comprising at least one light emitting diode (LED);

an accelerometer;

an adhesive layer configured to adhere to skin of a chest of an individual;

one or more rigid components connected to the adhesive layer, the one or more rigid components comprising a hardware processor for communication with the PPG sensor, the hardware processor configured to receive a plurality of measurements from each of the PPG sensor, wherein:

the hardware processor is configured to determine a plurality of cardiorespiratory parameters via chest accelerometry;

the hardware processor is further configured to determine inertial measures of thoracoabdominal movement; and

the plurality of cardiorespiratory parameters are determined based at least in part on the inertial measures of thoracoabdominal movement; and

an air gap between a lower surface of the adhesive layer and a lower surface of the PPG sensor for providing a compressive downward force when the adhesive layer and the PPG sensor are in contact with the skin of the chest of the individual, thereby improving signal quality of the PPG sensor, wherein:

the PPG sensor passes through the adhesive layer;

the adhesive layer and the PPG sensor are configured to be in contact with the skin of the chest of the individual simultaneously with at least a portion of the air gap therebetween; and

the hardware processor is further configured to:

measure, via the PPG sensor, cutaneous blood flow and volume; and

determine blood oxygen saturation (SpO2) derived from the cutaneous blood flow and volume.

Assignments (1)

Continuity (5)

References Cited (291)