Axial lengthening thrombus capture system
Systems and methods can remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebrovascular embolism, and other vascular occlusions.
1 . A material capture system comprising:
a first shaft defining a central lumen, the central lumen defining a central longitudinal axis;
a second shaft configured to be positioned within the central lumen of the first shaft;
a body, a first end of the body defining an opening and a second end of the body fixedly attached to the second shaft; and
a radially expandable guide including a proximal portion and a distal portion, the distal portion being attached to the first end of the body at a circumference of the opening and the proximal portion being attached to the first shaft,
wherein the body and the radially expandable guide are configured to be transformed from a compressed configuration to an expanded configuration in which the first end of the body and the distal portion of the radially expandable guide are expanded and the opening of the body defines a radial center offset from the central longitudinal axis,
wherein the distal portion of the radially expandable guide forms a loop,
wherein the proximal portion includes one or more leg elements, the one or more leg elements extending axially along the first shaft, and
wherein the one or more leg elements are secured to an outer wall of the first shaft via a sleeve.
2 . The material capture system of claim 1 , wherein the one or more leg elements form a right angle with the loop.
3 . The material capture system of claim 1 , wherein the one or more leg elements form an obtuse angle with the loop.
4 . The material capture system of claim 1 , wherein the loop is a continuous loop.
5 . The material capture system of claim 1 , wherein the radially expandable guide includes a shape memory material such that at least the distal portion is configured to, when released from the compressed configuration, form an annular structure.
6 . The material capture system of claim 1 , wherein the radially expandable guide is formed from nitinol.
7 . The material capture system of claim 1 , wherein the body includes a tubular braided body.
8 . The material capture system of claim 1 , further comprising an outer sheath, wherein the radially expandable guide and the body are configured to be collapsed within the outer sheath in the compressed configuration.
9 . The material capture system of claim 8 , wherein the radially expandable guide is configured to transform to the expanded configuration when distally advanced relative to the outer sheath.
10 . A material capture system comprising:
a first shaft defining a central lumen, the central lumen defining a central longitudinal axis;
a second shaft configured to be positioned within the central lumen of the first shaft;
a tubular braided body, a first end of the tubular braided body defining an opening and a second end of the tubular braided body fixedly attached to the second shaft; and
an expandable nitinol capture guide including a proximal portion and a distal portion, the distal portion being attached to the first end of the tubular braided body at a circumference of the opening and the proximal portion being attached to the first shaft,
wherein the tubular braided body and the expandable nitinol capture guide are configured to be transformed from a compressed configuration to an expanded configuration in which the first end of the tubular braided body and the distal portion of the expandable nitinol capture guide are expanded and the opening of the tubular braided body defines a radial center offset from the central longitudinal axis,
wherein the proximal portion of the expandable nitinol capture guide includes one or more leg elements that are fixedly secured to the first shaft via a coupler.
11 . The material capture system of claim 10 ,
wherein the distal portion of the expandable nitinol capture guide forms a loop, and
wherein the one or more leg elements extend axially along the first shaft.
12 . The material capture system of claim 11 , wherein the one or more leg elements form an obtuse angle with the loop.
13 . The material capture system of claim 11 , wherein the loop is a continuous loop.
14 . The material capture system of claim 11 , wherein the one or more leg elements are secured to an outer wall of the first shaft via the coupler.
15 . The material capture system of claim 10 , further comprising an outer sheath, wherein the expandable nitinol capture guide and the tubular braided body are configured to be collapsed within the outer sheath in the compressed configuration.
16 . A material capture system comprising:
a first shaft defining a central lumen, the central lumen defining a central longitudinal axis;
a second shaft configured to be positioned within the central lumen of the first shaft;
a tubular body, a first end of the tubular body defining an opening and a second end of the tubular body fixedly attached to the second shaft; and
a radially expandable guide including a proximal portion and a distal portion, the distal portion forming a loop and being attached to the first end of the tubular body at a circumference of the opening,
wherein the tubular body and the radially expandable guide are configured to be transformed from a compressed configuration to an expanded configuration in which the first end of the tubular body and the distal portion of the radially expandable guide are expanded and the opening of the tubular body defines a radial center offset from the central longitudinal axis,
wherein the proximal portion of the radially expandable guide includes one or more leg elements that are fixedly secured to the first shaft, and
wherein the one or more leg elements axially overlap the first shaft when the tubular body and the radially expandable guide are in the expanded configuration.
17 . The material capture system of claim 16 , wherein the loop is a continuous loop.
18 . The material capture system of claim 16 , wherein the radially expandable guide is formed from nitinol.
19 . The material capture system of claim 16 , wherein the tubular body includes a tubular braided body.
20 . The material capture system of claim 16 , wherein the one or more leg elements are secured to the first shaft via a coupler.