IP Library Granted Patent US 12,616,489
Granted Patent B2
US 12,616,489 · App. 19/303,491 · Granted May 5, 2026

Systems and methods for removing undesirable material within a circulatory system during a surgical procedure

Inventors: Lishan Aklog (Scarsdale, NY); Michael J. Glennon (Braintree, MA)
Assignee: AngioDynamics, Inc.
A61B17/22A61B17/3207A61M1/3621A61M1/741A61M1/87A61B2017/22079A61B2017/22094A61M1/79A61M1/80A61M2202/0014
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,616,489
App. No.
19/303,491
Granted
May 5, 2026
Kind
B2
Abstract

A method for capturing dislodged vegetative growth during a surgical procedure is provided. The method includes maneuvering, into a circulatory system, a first cannula having a distal end and an opposing proximal end, such that the first cannula is positioned to capture the vegetative growth en bloc. A second cannula is positioned in fluid communication with the first cannula, such that a distal end of the second cannula is situated in spaced relation to the distal end of the first cannula. A suction force is provided through the distal end of the first cannula so as to capture the vegetative growth. Fluid removed by the suction force is reinfused through the distal end of the second cannula. Subsequent to becoming dislodged, the vegetative growth is captured by the first cannula. A method for capturing a vegetative growth during removal of a pacemaker lead is also provided.

Claims (47)

1 . A method comprising:

placing a first cannula at least partially within a vasculature;

aspirating at least a portion of an undesirable material and blood from the vasculature through the first cannula and into a first container in fluid communication with the first cannula;

coupling the first container to a filter assembly;

coupling the filter assembly to a second container;

flowing the aspirated undesirable material and the aspirated blood from the first container through a filter of the filter assembly, thereby filtering the aspirated undesirable material from the aspirated blood, to produce filtered blood in the second container, and wherein the aspirated undesirable material is capable of being viewed within the filter assembly;

coupling the second container with a second cannula; and

driving the filtered blood from the second container through the second cannula into the vasculature to reinfuse the filtered blood into the vasculature.

2 . The method of claim 1 , wherein the first container comprises a first reservoir configured to store the aspirated undesirable material and the aspirated blood, and the second container comprises a second reservoir configured to store the filtered blood.

3 . The method of claim 2 , wherein the first container and the second container each comprise a manually operated pump.

4 . The method of claim 3 , wherein the undesirable material is a pulmonary embolism.

5 . The method of claim 1 , wherein the filter assembly comprises an inlet configured to be in fluid communication with the first container and an outlet configured to be in fluid communication with the second container.

6 . The method of claim 1 , further comprising:

placing the second cannula in a spaced relation to the first cannula within the vasculature.

7 . The method of claim 1 , wherein the filter comprises at least two filter screens each filter screen having a different pore size.

8 . The method of claim 1 , wherein the flowing of the aspirated undesirable material and the aspirated blood from the first container through the filter of the filter assembly and into the second container is performed until substantially all of the aspirated undesirable material has been filtered from the aspirated blood.

9 . The method of claim 1 , further comprising:

determining to continue the flowing of the aspirated undesirable material and the aspirated blood from the first container through the filter of the filter assembly and into the second container until obtaining visual confirmation that substantially all of the aspirated undesirable material has been captured in the filter assembly.

10 . A method comprising:

placing a first cannula at least partially within a vasculature;

aspirating at least a portion of an undesirable material and blood from the vasculature through the first cannula and into a first container coupled to the first cannula;

coupling the first container to a first filter assembly and coupling a second container to the first filter assembly;

moving the aspirated undesirable material and the aspirated blood from the first container through a first filter of the first filter assembly into the second container, the first filter being configured to filter the aspirated undesirable material from the aspirated blood to produce filtered blood;

coupling the second container to a second filter assembly;

moving the filtered blood from the second container through a second filter of the second filter assembly, the second filter being configured to further filter the undesirable material from the filtered blood to produce a twice filtered blood;

driving the twice filtered blood through a second cannula to reinfuse the twice filtered blood into the vasculature.

11 . The method of claim 10 , wherein the first cannula is a reinforced cannula, the undesirable material is a pulmonary embolism, and the vasculature comprises at least a part of the pulmonary system.

12 . The method of claim 10 , further comprising:

viewing the aspirated undesirable material within the first filter assembly.

13 . The method of claim 12 , further comprising:

continuing to move the aspirated undesirable material and the aspirated blood from the first container through the first filter of the first filter assembly and into the second container until obtaining visual confirmation that substantially all of the aspirated undesirable material has been captured in the first filter assembly.

14 . The method of claim 13 , wherein the first filter assembly comprises a first filter membrane having a first pore size and the second filter comprises a second filter membrane having a second pore size that is different from the first pore size.

15 . A method comprising:

placing an aspiration cannula at least partially within a vasculature;

aspirating at least a portion of an undesirable material and blood from the vasculature through the aspiration cannula and into a first container coupled to the aspiration cannula;

coupling the first container in fluid communication with an inlet of a filter device, wherein the filter device comprises the inlet, an outlet and a filter membrane;

fluidly coupling the outlet of the filter device with a second container;

pulling the aspirated undesirable material and the aspirated blood from the first container through the filter membrane into the second container, the filter membrane being configured to filter substantially all of the aspirated undesirable material from the aspirated blood to produce filtered blood,

viewing the filtered undesirable material entrapped within the filter device;

fluidly coupling the second container with a reinfusion cannula; and

reinfusing the filtered blood from the second container through the second cannula into the vasculature.

16 . The method of claim 15 , wherein the pulling of the aspirated undesirable material and the aspirated blood from the first container through the filter membrane into the second container is performed for a desired duration of time.

17 . The method of claim 15 , wherein the pulling of the aspirated undesirable material and the aspirated blood from the first container through the filter membrane into the second container is performed until the aspirated undesirable material has been confirmed removed by the viewing of the filtered undesirable material entrapped within the filter device.

18 . The method of claim 15 , wherein the aspiration cannula is reinforced and configured to optimize navigation of the aspiration cannula through the vasculature, and the undesirable material comprises a pulmonary embolism.

19 . The method of claim 17 , further comprising:

placing the aspiration cannula coaxially over a guidewire.

20 . The method of claim 19 , wherein the aspiration cannula further comprises an expandable distal end defined by a funnel shape.

Assignments (3)
MERGER Recorded Jun 3, 2026
From: VORTEX MEDICAL INC.
To: ANGIODYNAMICS, INC.
Reel/Frame 074834/0009 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 28, 2026
From: VORTEX MEDICAL INC.
To: ANGIODYNAMICS, INC.
Reel/Frame 074782/0427 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 19, 2025
From: AKLOG, LISHAN; GLENNON, MICHAEL
To: VORTEX MEDICAL INC.
Reel/Frame 072055/0720 →
Continuity (11)
Continuation 19013019 · Jan 8, 2025
Continuation 18985608 · Dec 18, 2024
Continuation 18942929 · Nov 11, 2024
Continuation 18156211 · Jan 18, 2023
Continuation 16458529 · Jul 1, 2019
Continuation 15194990 · Jun 28, 2016
Continuation 14250486 · Apr 11, 2014
Continuation 13084675 · Apr 12, 2011
Continuation In Part 12187121 · Aug 6, 2008
Provisional Application 61015301 · Dec 20, 2007
Related Publication 20250380957A1 · Dec 18, 2025
References Cited (147)
US 3701433A · Krakauer · 1972 [cited by applicant]
US 3765536A · Rosenberg · 1973 [cited by applicant]
US 4033345A · Sorenson · 1977 [cited by applicant]
US 4038194A · Luceyk · 1977 [cited by applicant]
US 4056476A · Mouwen · 1977 [cited by applicant]
US 4087363A · Rosemeyer · 1978 [cited by applicant]
US 4411783A · Dickens · 1983 [cited by applicant]
US 4690762A · Katsura · 1987 [cited by applicant]
US 4834743A · Valerio · 1989 [cited by applicant]
US 4886487A · Solem · 1989 [cited by applicant]
US 4892529A · Valerio · 1990 [cited by applicant]
US 4919802A · Katsura · 1990 [cited by applicant]
US 4954251A · Barnes · 1990 [cited by applicant]
US 5011488A · Ginsburg · 1991 [cited by applicant]
US 5055198A · Shettigar · 1991 [cited by applicant]
US 5100376A · Blake, III · 1992 [cited by applicant]
US 5133703A · Boehringer · 1992 [cited by applicant]
US 5201703A · Gentelia · 1993 [cited by applicant]
US 5234403A · Yoda · 1993 [cited by applicant]
US 5312479A · Weinstein · 1994 [cited by applicant]
US 5372945A · Alchas · 1994 [cited by applicant]
US 5380314A · Herweck · 1995 [cited by applicant]
US 5407424A · Lafontaine · 1995 [cited by applicant]
US 5588958A · Cunningham · 1996 [cited by applicant]
US 5603700A · Daneshvar · 1997 [cited by applicant]
US 5618425A · Mitamura · 1997 [cited by applicant]
US 5695489A · Japuntich · 1997 [cited by applicant]
US 5722964A · Herweck · 1998 [cited by applicant]
US 5785700A · Olson · 1998 [cited by applicant]
US 5788661A · Japuntich · 1998 [cited by applicant]
US 6059745A · Gelbfish · 2000 [cited by applicant]
US 6200276B1 · Biesel · 2001 [cited by applicant]
US 6274055B1 · Zuk, Jr. · 2001 [cited by applicant]
US 6451257B1 · Flamer · 2002 [cited by applicant]
US 6558341B1 · Swisher · 2003 [cited by applicant]
US 6682656B2 · Rothman · 2004 [cited by applicant]
US 6719717B1 · Johnson · 2004 [cited by applicant]
US 6767353B1 · Shiber · 2004 [cited by applicant]
US 6773670B2 · Stringer · 2004 [cited by applicant]
US 6936060B2 · Hogendijk · 2005 [cited by applicant]
US 7217361B2 · Connor · 2007 [cited by applicant]
US 7279107B2 · Hoegberg · 2007 [cited by applicant]
US 7353956B2 · Lynn · 2008 [cited by applicant]
US 7429325B2 · Ingvarsson · 2008 [cited by applicant]
US 7497944B2 · Hoegberg · 2009 [cited by applicant]
US 7621407B2 · Herbst · 2009 [cited by applicant]
US 7713227B2 · Wholey · 2010 [cited by applicant]
US 7794420B2 · Perovitch · 2010 [cited by applicant]
US 7927400B2 · Graber · 2011 [cited by applicant]
US 7938820B2 · Webster · 2011 [cited by applicant]
US 8080086B2 · Graber · 2011 [cited by applicant]
US 8187465B2 · Nierich · 2012 [cited by applicant]
US 8535283B2 · Heaton · 2013 [cited by applicant]
US 8586324B2 · Leach · 2013 [cited by applicant]
US 8613717B2 · Aklog · 2013 [cited by examiner]
US D724179S · Keenan · 2015 [cited by applicant]
US 8992403B2 · Eberle · 2015 [cited by applicant]
US 9555353B2 · Graber · 2017 [cited by applicant]
US 9675914B2 · Rivera · 2017 [cited by applicant]
US 9815038B2 · Leach · 2017 [cited by applicant]
US 9827364B2 · Peticca · 2017 [cited by applicant]
US 9907899B2 · Kim · 2018 [cited by applicant]
US 9937448B2 · Yost · 2018 [cited by applicant]
US 10111999B2 · Muennich · 2018 [cited by applicant]
US 10197026B2 · Salsburey · 2019 [cited by applicant]
US 10213582B2 · Garrison · 2019 [cited by applicant]
US 10226263B2 · Look · 2019 [cited by applicant]
US 10226598B2 · Chou · 2019 [cited by applicant]
US 10390849B2 · Kugler · 2019 [cited by applicant]
US 10456555B2 · Garrison · 2019 [cited by applicant]
US 10500330B2 · Schwarz · 2019 [cited by applicant]
US 10682454B2 · Coulthard · 2020 [cited by applicant]
US 10967111B2 · Iida · 2021 [cited by applicant]
US 11065018B2 · Buck · 2021 [cited by applicant]
US 11154314B2 · Quick · 2021 [cited by applicant]
US 11253277B2 · Buck · 2022 [cited by applicant]
US 11259821B2 · Buck · 2022 [cited by applicant]
US 11266825B2 · Peter · 2022 [cited by applicant]
US 11439799B2 · Buck · 2022 [cited by applicant]
US 11457936B2 · Buck · 2022 [cited by applicant]
US 11553935B2 · Buck · 2023 [cited by applicant]
US 11554005B2 · Merritt · 2023 [cited by applicant]
US 11559382B2 · Merritt · 2023 [cited by applicant]
US 11589880B2 · Aklog · 2023 [cited by examiner]
US 11607478B2 · Gadrat · 2023 [cited by applicant]
US 11633272B2 · Buck · 2023 [cited by applicant]
US 11642209B2 · Merritt · 2023 [cited by applicant]
US 11883570B2 · Yao · 2024 [cited by applicant]
US 12171917B1 · Buck · 2024 [cited by applicant]
US 12245781B2 · Aklog · 2025 [cited by examiner]
US 12446904B2 · Aklog · 2025 [cited by examiner]
US 20010049486A1 · Evans · 2001 [cited by applicant]
US 20020138094A1 · Borillo · 2002 [cited by applicant]
US 20030144687A1 · Brady · 2003 [cited by applicant]
US 20040019310A1 · Hogendijk · 2004 [cited by applicant]
US 20040102697A1 · Evron · 2004 [cited by examiner]
US 20040102728A1 · Foster · 2004 [cited by applicant]
US 20040153118A1 · Clubb · 2004 [cited by examiner]
US 20050004534A1 · Lockwood · 2005 [cited by applicant]
US 20050189283A1 · Smit · 2005 [cited by applicant]
US 20060047301A1 · Ogle · 2006 [cited by applicant]
US 20060270974A1 · Goff · 2006 [cited by applicant]
US 20080314834A1 · Herbst · 2008 [cited by applicant]
US 20110009837A1 · Schreiner · 2011 [cited by applicant]
US 20140364833A1 · Christensen · 2014 [cited by applicant]
US 20150173782A1 · Garrison · 2015 [cited by applicant]
US 20150314057A1 · Labib · 2015 [cited by applicant]
US 20150352325A1 · Quick · 2015 [cited by applicant]
US 20160106353A1 · Schuetz · 2016 [cited by applicant]
US 20180042623A1 · Batiste · 2018 [cited by applicant]
US 20180338770A1 · Mogi · 2018 [cited by applicant]
US 20190015398A1 · Osborne · 2019 [cited by applicant]
US 20190184076A1 · Gourlay · 2019 [cited by applicant]
US 20200030504A1 · Igarashi · 2020 [cited by applicant]
US 20200046368A1 · Merritt · 2020 [cited by applicant]
US 20200164117A1 · Culhane · 2020 [cited by applicant]
US 20210093758A1 · Corrales · 2021 [cited by applicant]
US 20210186537A1 · Buck · 2021 [cited by applicant]
US 20210186812A1 · Pennie · 2021 [cited by applicant]
US 20210187244A1 · Buck · 2021 [cited by applicant]
US 20210315598A1 · Buck · 2021 [cited by applicant]
US 20210316127A1 · Buck · 2021 [cited by applicant]
US 20210402086A1 · Jokaji · 2021 [cited by applicant]
US 20220184290A1 · Herzlinger · 2022 [cited by applicant]
US 20220226555A1 · Sunenshine · 2022 [cited by applicant]
US 20220240959A1 · Quick · 2022 [cited by applicant]
US 20220346813A1 · Quick · 2022 [cited by applicant]
US 20220346814A1 · Quick · 2022 [cited by applicant]
US 20220387759A1 · Turovskiy · 2022 [cited by applicant]
US 20230015259A1 · Buck · 2023 [cited by applicant]
US 20230062809A1 · Merritt · 2023 [cited by applicant]
US 20230233311A1 · Merritt · 2023 [cited by applicant]
AU 2019321256A1 · 2021 [cited by applicant]
CA 3114285A1 · 2020 [cited by applicant]
CN 112867455A · 2021 [cited by applicant]
EP 0122748A1 · 1984 [cited by applicant]
EP 0518975B1 · 1997 [cited by applicant]
EP 3836855A4 · 2022 [cited by applicant]
EP 3362116B1 · 2023 [cited by applicant]
JP 1983112549A · 1983 [cited by applicant]
JP 2021534851A · 2021 [cited by applicant]
WO 1997009106A1 · 1997 [cited by applicant]
WO 2006029270A1 · 2006 [cited by applicant]
WO 2006100651A1 · 2006 [cited by applicant]
WO 2014093845A1 · 2014 [cited by applicant]
WO 2015071852A2 · 2015 [cited by applicant]
WO 2016067246A1 · 2016 [cited by applicant]