IP Library Granted Patent US 11,259,821
Granted Patent B2
US 11,259,821 · App. 17/357,558 · Granted Mar 1, 2022

Aspiration system with accelerated response

Inventors: Michael Buck (Menlo Park, CA); Julia Fox (San Carlos, CA); James Jacobs (Danville, CA)
Assignee: Imperative Care, Inc.
A61B17/22A61M39/06A61B2017/00367A61B2017/22045A61B2017/22079A61M2039/062
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Quick Facts
Patent No.
US 11,259,821
App. No.
17/357,558
Granted
Mar 1, 2022
Kind
B2
Abstract

An aspiration system exhibits an accelerated drop in negative pressure at the distal end of an aspiration catheter from the time of opening a valve. The system includes an aspiration pump in communication with a first chamber, and an aspiration catheter configured for placement into fluid communication with the first chamber by way of an elongate aspiration tube. A second chamber is provided between the aspiration tube and the catheter, and a valve is provided between the second chamber and the aspiration catheter. Upon opening of the valve with negative pressure at equilibrium in the first and second chambers, resistance to fluid flow between the second chamber and the distal end of the catheter is less than the resistance to fluid flow between the second chamber and the first chamber, causing a rapid aspiration into the second chamber.

Claims (82)

1. An aspiration system with accelerated response, comprising:

an aspiration pump in communication with a first chamber;

an aspiration catheter configured for placement into fluid communication with the first chamber by way of an aspiration tube;

a handle on the aspiration catheter;

a second chamber in between the aspiration tube and the catheter, the second chamber being carried by the handle;

a valve between the second chamber and the aspiration catheter; and

a hemostasis valve carried by the handle;

wherein upon opening of the valve with negative pressure in the first and second chambers, resistance to fluid flow between the second chamber and a distal end of the catheter is less than the resistance to fluid flow between the second chamber and the first chamber, causing a rapid aspiration into the second chamber.

2. An aspiration system as in claim 1 , further comprising a first control on the handle for opening the valve.

3. An aspiration system as in claim 2 , wherein the valve is normally closed and actuation of the first control momentarily opens the valve.

4. An aspiration system as in claim 2 , further comprising a second control for activating the pump.

5. An aspiration system as in claim 1 , wherein the hemostasis valve comprises a collapsible tubular sidewall defining a valve lumen, and a filament formed into a loop around the tubular sidewall and configured to collapse the valve lumen.

6. An aspiration system as in claim 5 , wherein the hemostasis valve further comprises a frame and a lever, and the filament has at least a first tail portion extending away from the loop, around a first fulcrum on the lever and is secured against axial movement with respect to the frame.

7. An aspiration system as in claim 6 , wherein the first tail portion is connected to the frame.

8. An aspiration system as in claim 6 , further comprising a second lever, and the filament further comprises a second tail portion extending from the loop, around a second fulcrum on the second lever and is connected to the frame.

9. An aspiration system as in claim 1 , wherein the aspiration tube is at least about 50 inches long.

10. An aspiration system as in claim 1 , wherein the second chamber is configured to capture a clot aspirated by the catheter.

11. An aspiration system as in claim 10 , wherein at least a portion of the second chamber is removably carried by the handle.

12. An aspiration system as in claim 11 , wherein the second chamber comprises a filter membrane spaced apart from a transparent wall.

13. An aspiration system as in claim 12 , comprising a tubular filter membrane, spaced radially inwardly apart from a transparent outer tubular wall.

14. An aspiration system as in claim 1 , further comprising an operator actuated control, configured to toggle a flow regulator between a default low flow mode, and a momentary, operator initiated high flow override mode.

15. An aspiration system as in claim 1 , wherein the second chamber is configured for location within a sterile field, and the first chamber is configured for location outside of the sterile field.

16. An aspiration system as in claim 1 , further comprising a tube between the handle and the second chamber, and the tube is no more than about 20 inches long.

17. An aspiration system with accelerated response, comprising:

an aspiration pump in communication with a first chamber;

an aspiration catheter configured for placement into fluid communication with the first chamber by way of an aspiration tube;

a second chamber in between the aspiration tube and the catheter, the second chamber being configured to capture a clot aspirated by the catheter, wherein at least a portion of the second chamber is removably carried by a handle; and

a valve between the second chamber and the aspiration catheter;

wherein upon opening of the valve with negative pressure in the first and second chambers, resistance to fluid flow between the second chamber and a distal end of the catheter is less than the resistance to fluid flow between the second chamber and the first chamber, causing a rapid aspiration into the second chamber.

18. An aspiration system as in claim 17 , further comprising a handle on the aspiration catheter, and the second chamber is carried by the handle.

19. An aspiration system as in claim 18 , further comprising a first control on the handle for opening the valve.

20. An aspiration system as in claim 19 , wherein the valve is normally closed and actuation of the first control momentarily opens the valve.

21. An aspiration system as in claim 19 , further comprising a second control for activating the pump.

22. An aspiration system as in claim 18 further comprising a hemostasis valve carried by the handle, wherein the hemostasis valve comprises a collapsible tubular sidewall defining a valve lumen, and a filament formed into a loop around the tubular sidewall and configured to collapse the valve lumen.

23. An aspiration system as in claim 22 , wherein the hemostasis valve further comprises a frame and a lever, and the filament has at least a first tail portion extending away from the loop, around a first fulcrum on the lever and is secured against axial movement with respect to the frame.

24. An aspiration system as in claim 23 , wherein the first tail portion is connected to the frame.

25. An aspiration system as in claim 23 , further comprising a second lever, and the filament further comprises a second tail portion extending from the loop, around a second fulcrum on the second lever and is connected to the frame.

26. An aspiration system as in claim 17 , wherein the aspiration tube is at least about 50 inches long.

27. An aspiration system as in claim 17 , wherein the second chamber comprises a filter membrane spaced apart from a transparent wall.

28. An aspiration system as in claim 27 , comprising a tubular filter membrane, spaced radially inwardly apart from a transparent outer tubular wall.

29. An aspiration system as in claim 17 , further comprising an operator actuated control, configured to toggle a flow regulator between a default low flow mode, and a momentary, operator initiated high flow override mode.

30. An aspiration system as in claim 17 , wherein the second chamber is configured for location within a sterile field, and the first chamber is configured for location outside of the sterile field.

31. An aspiration system as in claim 17 , further comprising a tube between the handle and the second chamber, and the tube is no more than about 18 inches long.

32. An aspiration system with accelerated response, comprising:

an aspiration pump in communication with a first chamber;

an aspiration catheter configured for placement into fluid communication with the first chamber by way of an aspiration tube;

a second chamber in between the aspiration tube and the catheter;

a valve between the second chamber and the aspiration catheter; and

an operator actuated control, configured to toggle a flow regulator between a default low flow mode, and a momentary, operator initiated high flow override mode;

wherein upon opening of the valve with negative pressure in the first and second chambers, resistance to fluid flow between the second chamber and a distal end of the catheter is less than the resistance to fluid flow between the second chamber and the first chamber, causing a rapid aspiration into the second chamber.

33. An aspiration system as in claim 32 , further comprising a handle on the aspiration catheter, and the second chamber is carried by the handle.

34. An aspiration system as in claim 33 , further comprising a first control on the handle for opening the valve.

35. An aspiration system as in claim 34 , wherein the valve is normally closed and actuation of the first control momentarily opens the valve.

36. An aspiration system as in claim 34 , further comprising a second control for activating the pump.

37. An aspiration system as in claim 33 further comprising a hemostasis valve carried by the handle, wherein the hemostasis valve comprises a collapsible tubular sidewall defining a valve lumen, and a filament formed into a loop around the tubular sidewall and configured to collapse the valve lumen.

38. An aspiration system as in claim 37 , wherein the hemostasis valve further comprises a frame and a lever, and the filament has at least a first tail portion extending away from the loop, around a first fulcrum on the lever and is secured against axial movement with respect to the frame.

39. An aspiration system as in claim 38 , wherein the first tail portion is connected to the frame.

40. An aspiration system as in claim 38 , further comprising a second lever, and the filament further comprises a second tail portion extending from the loop, around a second fulcrum on the second lever and is connected to the frame.

41. An aspiration system as in claim 32 , wherein the aspiration tube is at least about 50 inches long.

42. An aspiration system as in claim 32 , wherein the second chamber is configured to capture a clot aspirated by the catheter, wherein at least a portion of the second chamber is removably carried by a handle, and wherein the second chamber comprises a filter membrane spaced apart from a transparent wall.

43. An aspiration system as in claim 42 , comprising a tubular filter membrane, spaced radially inwardly apart from a transparent outer tubular wall.

44. An aspiration system as in claim 32 , wherein the second chamber is configured for location within a sterile field, and the first chamber is configured for location outside of the sterile field.

45. An aspiration system as in claim 32 , further comprising a handle on the aspiration catheter, a tube between the handle and the second chamber, and the tube is no more than about 20 inches long.

46. An aspiration system with accelerated response, comprising:

an aspiration pump in communication with a first chamber;

an aspiration catheter configured for placement into fluid communication with the first chamber by way of an aspiration tube;

a second chamber in between the aspiration tube and the catheter; and

a valve between the second chamber and the aspiration catheter;

wherein upon opening of the valve with negative pressure in the first and second chambers, resistance to fluid flow between the second chamber and a distal end of the catheter is less than the resistance to fluid flow between the second chamber and the first chamber, causing a rapid aspiration into the second chamber, and

wherein the second chamber is configured for location within a sterile field, and the first chamber is configured for location outside of the sterile field.

47. An aspiration system as in claim 46 , further comprising a handle on the aspiration catheter, and the second chamber is carried by the handle.

48. An aspiration system as in claim 47 , further comprising a first control on the handle for opening the valve.

49. An aspiration system as in claim 48 , wherein the valve is normally closed and actuation of the first control momentarily opens the valve.

50. An aspiration system as in claim 48 , further comprising a second control for activating the pump.

51. An aspiration system as in claim 47 further comprising a hemostasis valve carried by the handle, wherein the hemostasis valve comprises a collapsible tubular sidewall defining a valve lumen, and a filament formed into a loop around the tubular sidewall and configured to collapse the valve lumen.

52. An aspiration system as in claim 51 , wherein the hemostasis valve further comprises a frame and a lever, and the filament has at least a first tail portion extending away from the loop, around a first fulcrum on the lever and is secured against axial movement with respect to the frame.

53. An aspiration system as in claim 52 , wherein the first tail portion is connected to the frame.

54. An aspiration system as in claim 52 , further comprising a second lever, and the filament further comprises a second tail portion extending from the loop, around a second fulcrum on the second lever and is connected to the frame.

55. An aspiration system as in claim 46 , wherein the aspiration tube is at least about 50 inches long.

56. An aspiration system as in claim 46 , wherein the second chamber is configured to capture a clot aspirated by the catheter, wherein at least a portion of the second chamber is removably carried by a handle, and wherein the second chamber comprises a filter membrane spaced apart from a transparent wall.

57. An aspiration system as in claim 56 , comprising a tubular filter membrane, spaced radially inwardly apart from a transparent outer tubular wall.

58. An aspiration system as in claim 46 , further comprising a handle on the aspiration catheter, a tube between the handle and the second chamber, and the tube is no more than about 20 inches long.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 8, 2021
From: BUCK, MICHAEL; FOX, JULIA; JACOBS, JAMES
To: IMPERATIVE CARE, INC.
Reel/Frame 056792/0138 →
Continuity (5)
Continuation In Part 17125723 · Dec 17, 2020
Provisional Application 63064273 · Aug 11, 2020
Provisional Application 63044511 · Jun 26, 2020
Provisional Application 62950058 · Dec 18, 2019
Related Publication 20210315597A1 · Oct 14, 2021
Cited By (37)
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