IP Library › Granted Patent US 6,875,431
Granted Patent B2
US 6,875,431 · App. 10/135,824 · Granted Apr 5, 2005

Method for the treatment of bacterial eye infections

Assignees: New Horizons Diagnostics Corp.; Rockefeller University
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Quick Facts
Patent No.
US 6,875,431
App. No.
10/135,824
Granted
Apr 5, 2005
Kind
B2
Abstract

A method for treatment of bacterial infections of the eye is disclosed which comprises a lytic enzyme composition specific for the infecting bacteria, and a carrier for delivering said lytic enzyme. The composition may be in the form of an isotonic solution.

Claims (8)

1. A method for treating bacterial infections of an eye, wherein the method comprises delivering to said eye a composition comprising:

(i) an effective amount of at least one lytic enzyme genetically coded for by a bacteriophage specific for a bacteria that causes said bacterial infections of said eye, said at least one lytic enzyme having the ability to digest a cell wall of a specific said bacterial: and,

ii) a carrier for delivering said enzyme to said eye.

2. The method according to claim 1 wherein said bacteria being treated is Hemophilus.

3. The method according to claim 1 , wherein said bacteria being treated is Staphylococcus.

4. The method according to claim 1 , wherein the carrier is an eye drop solution.

5. The method according to claim 1 , wherein the carrier is en eye wash solution.

6. The method according to claim 1 , wherein the carrier is an isotonic solution.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 14, 2003
From: FISCHETTI, VINCENT A.; NEW HORIZONS DIAGNOSTICS CORPORATION
To: ROCKEFELLER UNIVERSITY, THE
Reel/Frame 014043/0389 →
Continuity (5)
Continuation 0967188100 · Sep 28, 2000
Continuation In Part 0949749500 · Apr 18, 2000
Continuation 0939563600 · Sep 14, 1999
Continuation In Part 0896252300 · Oct 31, 1997
Related Publication 20020146403A1 · Oct 10, 2002