Granted Patent
B2
US 6,903,073 · App. 09/733,634 · Granted Jun 7, 2005
Methods to stimulate insulin production by pancreatic beta-cells
Assignee:
The General Hospital Corporation
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Abstract
The invention features a method of treating deficiency of insulin in a patient, comprising administering to a patient in need thereof hedgehog protein or nucleic acid in an amount effective to raise the level of insulin in the patient.
Claims (2)
1. A method of treating deficiency of insulin in a patient, comprising administering to a patient in need thereof a nucleic acid encoding hedgehog protein, said hedgehog protein being one of desert hedgehog, indian hedgehog, or sonic hedgehog, in an amount effective to raise the level of insulin in said patient.
2. The method of claim 1 , wherein said patient is afflicted with diabetes.
Assignments (4)
CONFIRMATORY LICENSE
Recorded Jun 22, 2015
From: MASSACHUSETTS GENERAL HOSPITAL
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 035989/0024 →
CONFIRMATORY LICENSE
Recorded Jul 30, 2010
From: MASSACHUSETTS GENERAL HOSPITAL
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 024770/0165 →
CONFIRMATORY LICENSE
Recorded Aug 5, 2008
From: GENERAL HOSPITAL CORPORATION DBA MASS
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 021338/0124 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Apr 23, 2001
From: HABENER, JOEL F.; THOMAS, MELISSA K.
To: GENERAL HOSPITAL CORPORATION, THE
Reel/Frame 011738/0193 →
Continuity (2)
Provisional Application
6017028200
· Dec 10, 1999