IP Library › Granted Patent US 6,903,189
Granted Patent B2
US 6,903,189 · App. 09/813,718 · Granted Jun 7, 2005

Human aminoacyl-tRNA synthetase polypeptides useful for the regulation of angiogenesis

Assignee: The Scripps Research Institute
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Quick Facts
Patent No.
US 6,903,189
App. No.
09/813,718
Granted
Jun 7, 2005
Kind
B2
Abstract

The invention provides compositions comprising truncated tryptophanyl tRNA synthetase polypeptides useful for regulating angiogenesis, as well as nucleic acids encoding such truncated tRNA synthetase polypeptides. Methods of making and using such compositions are also disclosed.

Claims (3)

1. An isolated polypeptide consisting of amino acid residues 71-471 of SEQ ID NO:10.

2. The isolated polypeptide of claim 1 produced by cleavage of the polypeptide consisting essentially of residues 1-471 of SEQ ID NO:10 with polymorphonuclear leucocyte elastase.

3. A composition comprising the isolated polypeptide of claim 1 and a pharmaceutically suitable excipient.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 23, 2001
From: SCHIMMEL, PAUL
To: SCRIPPS RESEARCH INSTITUTE, THE
Reel/Frame 012000/0178 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 20, 2001
From: WAKASUGI, KEISUKE
To: SCRIPPS RESEARCH INSTITUTE, THE
Reel/Frame 012028/0586 →
Continuity (1)
Related Publication 20020182666A1 · Dec 5, 2002