IP Library Granted Patent US 6,975,900
Granted Patent B2
US 6,975,900 · App. 10/317,953 · Granted Dec 13, 2005

Systems and methods for determining a surface geometry

Assignee: Case Western Reserve University
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Quick Facts
Patent No.
US 6,975,900
App. No.
10/317,953
Granted
Dec 13, 2005
Kind
B2
Abstract

Methods and systems for determining a surface geometry of an object, including determining a first projection matrix based on a first imaging device, determining a second projection matrix based on a second imaging device, obtaining at least one first two-dimensional (2D) image of the object using the first imaging device, obtaining at least one second 2D image of the object using the second imaging device, determining a contour of the object in the first 2D image and the second 2D image, and, based on the at least two contours, the first projection matrix, and the second projection matrix, reconstructing 3D data associated with the surface of the object. In one embodiment, the object can be a heart.

Claims (18)

1. A method for computing epicardial surface electric potentials based on measured body surface electric potentials, the method comprising:

generating a multidimensional matrix, the matrix representing at least one geometric relationship between at least one body surface electric potential measuring system and the epicardial surface, the multidimensional matrix being based on:

at least one first two-dimensional (2D) image of the epicardium using a first imaging device,

at least one second 2D image of the epicardium using a second imaging device,

a first projection matrix associated with the first imaging device,

a second projection matrix associated with the second imaging device,

a computed contour of the outer surface of the heart formed from contours identified in the at least one first 2D image and the at least one second 2D image,

a computed contour of the electric potential measuring system, and,

a boundary element method based on the computed contour of the outer surface of the heart and the computed contour of the electric potential measuring system,

using a Generalized Minimum Residual (GMRes) method to estimate an inverse of the multidimensional matrix, and,

based on the inverse matrix and the measured body surface potentials, determining the epicardial surface electric potentials.

2. A method according to claim 1 , where representing includes measuring the position of the at least one body surface electric potential measuring system.

3. A method according to claim 1 , where using a GMRes method includes determining a number of iterations for the GMRes method.

4. A method according to claim 3 , where using a GMRes method includes providing a maximum number of iterations for the GMRes method, and based on the data from the maximum number of iterations, determining a number of iterations for the GMRes method.

5. A method according to claim 3 , where determining a number of iterations includes comparing residual error to a Hessenberg matrix condition, and computing at least one of a corner of a condition L curve and a maximum curvature of a condition L curve.

6. A method according to claim 3 , where determining a number of iterations includes determining a number of iterations based on at least one of: a corner of a condition L curve, a corner of an L curve, an increase in spatial frequency of a reconstructed potential map, and an increase in amplitude of a solution norm.

7. A method according to claim 1 , where using a GMRes method includes providing an initial condition of zero.

8. A method according to claim 1 , where using a GMRes method includes providing an initial condition based on a Tikhonov regularization of the multidimensional matrix.

Assignments (3)
CONFIRMATORY LICENSE Recorded Oct 1, 2008
From: CASE WESTERN RESERVE UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 021616/0167 →
CORRECT ASSIGNMENT TO REPLACE ASSIGNOR'S NAME RAJA CHANEM WITH RAJA GHANEM PREVIOUSLY RECORDED ON REEL 013753, FRAME 0341. Recorded Jul 11, 2003
From: RUDY, YORAM; RAMANATHAN, CHARULATHA; GHANEM, RAJA; JIA, PING
To: CASE WESTERN RESERVE UNIVERSITY
Reel/Frame 014256/0273 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 23, 2003
From: RUDY, YORAM; RAMANATHAN, CHARULATHA; CHANEM, RAJA; JIA, PING
To: CASE WESTERN RESERVE UNIVERSITY
Reel/Frame 013753/0341 →
Continuity (6)
Continuation In Part 1026457200 · Oct 4, 2002
Continuation In Part 1003760300 · Oct 19, 2001
Continuation 0946342800
Provisional Application 6032741900 · Oct 4, 2001
Provisional Application 6005434200 · Jul 31, 1997
Related Publication 20040082870A1 · Apr 29, 2004