IP Library › Granted Patent US 7,125,905
Granted Patent B2
US 7,125,905 · App. 11/028,477 · Granted Oct 24, 2006

Pyrrole substituted 2-indolinone protein kinase inhibitors

Assignee: Agouron Pharmaceuticals, Inc.
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Quick Facts
Patent No.
US 7,125,905
App. No.
11/028,477
Granted
Oct 24, 2006
Kind
B2
Abstract

The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

Claims (2)

1. A compound that is the L-malate salt of 5-(5-fluoro-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide.

2. A pharmaceutical composition comprising the compound of claim 1 and a pharmaceutically acceptable carrier or excipient.

Continuity (6)
Continuation 1041269000 · Apr 14, 2003
Division 0978326400 · Feb 15, 2001
Provisional Application 6018271000 · Feb 15, 2000
Provisional Application 6021642200 · Jul 6, 2000
Provisional Application 6024353200 · Oct 27, 2000
Related Publication 20050176802A1 · Aug 11, 2005