Surface topography for non-toxic bioadhesion control
View Patent ↗A coated surface for resisting or enhancing bioadhesion includes at least one patterned polymer including coating layer having a plurality of features attached to or projected into a base surface. The features each have at least one microscale (<1 mm) dimension and have at least one neighboring feature having a substantially different geometry. The patterned coating layer preferably provides an average roughness factor (R) of from 4 to 50. The coating layer resists or enhances bioadhesion as compared to the base surface.
1. A coated surface topography for resisting bioadhesion, comprising:
at least one coating layer that comprises a polymer, said coating layer having a pattern defined by a plurality of spaced apart features attached to or projected into a base surface, said plurality of features each having at least one microscale dimension and having at least one neighboring feature having a substantially different geometry, wherein an average spacing between adjacent ones of said features is between 0.5 and 5 μm in at least a portion of said coating layer, said coating layer resisting bioadhesion as compared to said base surface.
2. The coated surface of claim 1 , wherein a chemical composition of said coating layer is different as compared to a composition of said base surface.
3. The coated surface of claim 1 , wherein said coating layer comprises a non-electrically conductive material.
4. The coating of claim 1 , wherein said coating layer provides an average roughness factor (R) of from 4 to 50.
5. The coating of claim 1 , wherein an elastic modulus of said coating layer is between 10 kPa and 10 MPa.
6. The coating of claim 1 , wherein said plurality of spaced apart features have a substantially planar top surface.
7. The coating of claim 1 , wherein said spacing is between 0.5 and 2 μm.
8. The coating of claim 1 , further comprising at least one multi-element plateau layer disposed on a portion of said coating layer, wherein a spacing distance between elements of said plateau layer provide a second feature spacing being substantially different as compared to said first feature spacing.
9. The coating of claim 1 , wherein said polymer comprises at least one selected from the group consisting of elastomers, rubbers, polyurethanes and polysulfones.
10. An article having a surface coating with topography for controlling bioadhesion, comprising:
a base surface; and
at least one coating layer that comprises a polymer, said coating layer having a pattern defined by a plurality of spaced apart features attached to or projected into a base surface, said plurality of features each having at least one microscale dimension and having at least one neighboring feature having a substantially different geometry, wherein an average spacing between adjacent ones of said features is between 0.5 and 5 μm in at least a portion of said coating layer, said coating layer resisting bioadhesion as compared to said base surface.
11. The article of claim 10 , wherein said base surface comprises a roofing material.
12. The article of claim 10 , wherein said base surface comprises an inner surface of a water inlet pipe for a power plants.
13. The article of claim 10 , wherein said base surface comprises an implantable device or material.
14. The article of claim 13 , wherein said implantable device or material comprises a breast implant, a catheter or a heart valve.
15. The article of claim 10 , further comprising at least one multi-element plateau layer disposed on a portion of said coating layer, wherein a spacing distance between elements of said plateau layer provide a second feature spacing being substantially different as compared to said first feature spacing.
16. The article of claim 10 , wherein an elastic modulus of said coating layer is between 10 kPa and 10 MPa.
17. The article of claim 10 , wherein said plurality of spaced apart features have a substantially planar top surface.
18. The article of claim 10 , wherein said coating layer provides an average roughness factor (R) of from 4 to 50.