IP Library Granted Patent US 7,166,076
Granted Patent B2
US 7,166,076 · App. 10/935,698 · Granted Jan 23, 2007

Vascular testing system

Assignee: BioMedix, Inc.
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Quick Facts
Patent No.
US 7,166,076
App. No.
10/935,698
Granted
Jan 23, 2007
Kind
B2
Abstract

A vascular testing system includes a pressure applicator, a pressure source for generating fluid pressure at the pressure applicator; a variable orifice valve, and a valve control. The variable orifice valve is in fluid communication with the pressure applicator, and has an orifice size capable of dynamically changing. The valve control controls the variable orifice valve as a function of sensed pressure to produce substantially linear changes in pressure at the pressure applicator. Further, a method of vascular pressure measurement according to the present invention includes providing an applied pressure higher than a patient's systolic blood pressure at a vascular location, substantially linearly decreasing the applied pressure at the vascular location, and dynamically detecting vascular pressure oscillations at the vascular location as the applied pressure is decreased.

Claims (18)

1. A vascular testing system comprising:

a pressure applicator;

a pressure source for generating fluid pressure at the pressure applicator;

a variable orifice valve in fluid communication with the pressure applicator, wherein the valve has an orifice size capable of dynamically changing;

a pressure sensor operably connected between the pressure applicator and the variable orifice valve;

a valve control for controlling the variable orifice valve as a function of pressure sensed by the pressure sensor to produce substantially linear changes in pressure at the pressure applicator; and

a control device for causing the vascular testing system to determine a peak pressure oscillation amplitude as a function of pressure sensed by the pressure sensor as pressure applied by the pressure applicator is lessened, and to determine a first pressure value that corresponds to a pressure oscillation amplitude at approximately seventy-five percent (75%) of a peak pressure oscillation amplitude and at a pressure greater than a pressure value corresponding to the peak pressure oscillation amplitude, and to produce an output of the first pressure value identified as a pressure at a return of blood flow at a vascular location adjacent the pressure applicator.

2. The vascular testing system of claim 1 , wherein the pressure applicator is an oscillometric pressure cuff.

3. The vascular testing system of claim 2 , wherein the oscillometric pressure cuff is sized to fit on a human toe.

4. A method of vascular pressure measurement, the method comprising:

providing an applied pressure at a vascular location, wherein the applied pressure is higher than a patient's systolic blood pressure;

substantially linearly decreasing the applied pressure at the vascular location;

dynamically detecting vascular pressure oscillations at the vascular location as the applied pressure is decreased;

determining a first pressure value corresponding to an oscillation amplitude of about seventy-five percent (75%) of a peak value of a curve approximating the vascular pressure oscillations, wherein the first pressure value is higher than a pressure value corresponding to the peak value of the curve approximating the vascular pressure oscillations;

generating an output that corresponds to the first pressure value; and

identifying the output as a return of blood flow pressure at the vascular location.

5. The method of claim 4 , wherein an orifice size of a variable orifice valve is changed over time for linearly decreasing the applied pressure at the vascular location.

6. The method of claim 4 , wherein the vascular location is disposed at a human toe.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 15, 2014
From: BIOMEDIX VASCULAR SOLUTIONS, INC.
To: COLLABORATIVE CARE DIAGNOSTICS, LLC
Reel/Frame 032674/0183 →
MERGER Recorded Apr 15, 2014
From: BIOMEDIX, INC.
To: BIOMEDIX VASCULAR SOLUTIONS, INC.
Reel/Frame 032689/0082 →
CORRECTED RESUBMISSION RECORDATION COVER SHEET Recorded Dec 30, 2004
From: POLIAC, MARIUS; BLANCH, GARY WARNER; GLAVA, VICTOR FLORIN; INCE, DANIEL JAMES; KARLES, ANDREW PAUL; ROGERS, WILLIAM LEE; ROMANS, JOHN ALEXANDER; SIERS, MICHAEL JEROME; STEADERMAN, CHARLES FREDREC; GRAVE, RICKY LEE
To: BIOMEDIX, INC.
Reel/Frame 016763/0601 →
Continuity (1)
Related Publication 20060052713A1 · Mar 9, 2006