IP Library Granted Patent US 7,196,245
Granted Patent B2
US 7,196,245 · App. 10/666,642 · Granted Mar 27, 2007

Polynucleotides and polypeptides that confer increased biomass and tolerance to cold, water deprivation and low nitrogen to plants

Assignee: Mendel Biotechnology, Inc.
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Quick Facts
Patent No.
US 7,196,245
App. No.
10/666,642
Granted
Mar 27, 2007
Kind
B2
Abstract

The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties compared to a reference plant. These properties include increased biomass and increased tolerance to cold, water deprivation, and low nitrogen conditions.

Claims (28)

1. A transgenic plant transformed with an expression vector comprising a polynucleotide sequence encoding a polypeptide having a conserved domain that has at least 70% sequence identity to the conserved domain of amino acid coordinates 111–164 of SEQ ID NO: 194, wherein the conserved domain is a WRKY DNA-binding domain and expression of the polynucleotide in said transgenic plant results in said plant having a greater tolerance to water deprivation than a control plant.

2. The transgenic plant of claim 1 , wherein the expression vector further comprises a constitutive, inducible, or tissue-specific promoter operably linked to the polynucleotide sequence.

3. A seed produced by the transgenic plant according to claim 1 , wherein the seed comprises the polynucleotide sequence of claim 1 .

4. A method for producing a transgenic plant having greater tolerance to water deprivation than a control plant, the method steps comprising:

(a) providing an expression vector comprising:

(i) a polynucleotide sequence encoding a polypeptide comprising a conserved domain that has at least 70% sequence identity to the conserved domain of amino acid coordinates 111–164 of SEQ ID NO: 194, wherein the conserved domain is a WRKY DNA-binding domain and expression of the polynucleotide in said transgenic plant results in said plant having a greater tolerance to water deprivation than a control plant; and

(ii) at least one regulatory element operably linked to the polynucleotide sequence, wherein said at least one regulatory element controls expression of the polynucleotide sequence in a target plant;

(b) introducing the expression vector into at least one plant; and

(c) selecting at least one transgenic plant that has greater tolerance to water deprivation than the control plant.

5. The method of claim 4 , wherein the polypeptide comprises a conserved domain that has at least 80% sequence identity to the conserved domain of amino acid coordinates 111–164 of SEQ ID NO: 194 wherein the conserved domain is a WRKY DNA-binding domain and expression of the polynucleotide in the transgenic plant results in said plant having a greater tolerance to water deprivation than a control plant.

6. The method of claim 4 , wherein the polypeptide comprises a conserved domain that has at least 85% sequence identity to the conserved domain of amino acid coordinates 111–164 of SEQ ID NO: 194 wherein the conserved domain is a WRKY DNA-binding domain and expression of the polynucleotide in the transgenic plant results in said plant having a greater tolerance to water deprivation than a control plant.

7. The method of claim 4 , wherein the regulatory element is a cauliflower mosaic virus 35S promoter.

8. The method of claim 4 , wherein the regulatory element is a root-specific, epidermis-specific, meristem-specific, vascular-specific or leaf-specific promoter.

9. The method of claim 4 , wherein the regulatory element is a drought-inducible or cold-inducible promoter.

10. The method of claim 4 , wherein the transgenic plant has greater tolerance to 168 hours without watering than the control plant.

11. A seed produced by a transgenic plant produced by the method according to claim 4 , wherein the seed comprises the expression vector of claim 4 .

12. A method for increasing the tolerance of a plant to water deprivation, the method steps comprising:

(a) providing an expression vector comprising:

(i) a polynucleotide sequence encoding a polypeptide comprising a conserved domain that has at least 70% sequence identity to the conserved domain of amino acid coordinates 111–164 of SEQ ID NO: 194, wherein the conserved domain is a WRKY DNA-binding domain and expression of the polynucleotide in the transgenic plant results in said plant having a greater tolerance to water deprivation than a control plant; and

(ii) at least one regulatory element flanking the polynucleotide sequence, wherein said at least one regulatory element controls expression of the polynucleotide sequence in a target plant;

(b) introducing the expression vector into a plant, thereby producing a transgenic plant; and

(c) selecting a transgenic plant having greater tolerance to water deprivation than a control plant.

13. The method of claim 12 , wherein the polypeptide comprises a conserved domain that has at least 80% sequence identity to the conserved domain of amino acid coordinates 111–164 of SEQ ID NO: 194 wherein the conserved domain is a WRKY DNA-binding domain and expression of the polynucleotide in the transgenic plant results in said plant having a greater tolerance to water deprivation than a control plant.

14. The method of claim 12 , wherein the polypeptide comprises a conserved domain that has at least 85% sequence identity to the conserved domain of amino acid coordinates 111–164 of SEQ ID NO: 194 wherein the conserved domain is a WRKY DNA-binding domain and expression of the polynucleotide in the transgenic plant results in said plant having a greater tolerance to water deprivation than a control plant.

15. The method of claim 12 , wherein the transgenic plant has greater tolerance to 168 hours without watering than the control plant.

16. The transgenic plant of claim 1 , where in the polynucleotide sequence comprises SEQ ID NO: 193.

17. The method of claim 4 , where in the polynucleotide sequence comprises SEQ ID NO: 193.

18. The method of claim 12 , where in the polynucleotide sequence comprises SEQ ID NO: 193.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 2, 2004
From: JIANG, CAI-ZHONG; HEARD, JACQUELINE E.; RATCLIFFE, OLIVER; CREELMAN, ROBERT A.; ADAM, LUC J.; REUBER, T. LYNNE; RIECHMANN, JOSE LUIS; HAAKE, VOLKER; DUBELL III, ARNOLD N.; KEDDIE, JAMES S.; SHERMAN, BRADLEY K.
To: MENDEL BIOTECHNOLOGY, INC.
Reel/Frame 014312/0278 →
Continuity (4)
Provisional Application 6046580900 · Apr 24, 2003
Provisional Application 6043416600 · Dec 17, 2002
Provisional Application 6041183700 · Sep 18, 2002
Related Publication 20070033671A1 · Feb 8, 2007