Cosmetic and dermatological light protection formulations with a content of hydroxybenzophenones and alkylnaphthalates
The invention relates to light-protective cosmetic or dermatological preparations that contain (a) at least one hydroxy-benzophenone, and (b) at last one dialkyl naphthalate of the structural formula (I), wherein R 1 and R 2 are independently selected form the group of the branched and unbranched alkyl groups that have 6 to 24 carbon atoms. The invention further relates to the use of said formulations
1. Light-protective cosmetic or dermatological preparation, comprising:
(a) at least one hydroxybenzophenone of the following structural formula:
where
R 1 and R 2 independent of one another are hydrogen, C 1 –C 20 -alkyl, C 3 –C 10 -cycloalkyl or C 3 –C 10 -cyloalkenyl, wherein the substituents R 1 and R 2 together with the nitrogen atom to which they are bound can form a 5- or 6-ring, and
R 3 is a C 1 –C 20 alkyl radical, and
(b) at least one dialkyl naphthalate comprising the structural formula
where R 1 and R 2 are independently one of branched and unbranched alkyl groups with 6 to 24 carbon atoms.
2. Light-protective cosmetic or dermatological preparation, comprising synergistic substance combinations of
(a) at least one hydroxybenzophenone of the following structural formula:
where
R 1 and R 2 independent of one another are hydrogen, C 1 –C 20 -alkyl, C 3 –C 10 -cycloalkyl or C 3 –C 10 -cyloalkenyl, wherein the substituents R 1 and R 2 together with the nitrogen atom to which they are bound can form a 5- or 6-ring, and
R 3 is a C 1 –C 20 alkyl radical, and
(b) at least one dialkyl naphthalate comprising the structural formula
where R 1 and R 2 are independently one of branched and unbranched alkyl groups with 6 to 24 carbon atoms,
wherein UV protective effect, in particular UVA protective effect, of the preparation is higher than that of the same preparation that does not contain any substances according to (b).
3. Preparation according to claim 1 , wherein the at least one dialkyl naphthalate is present in a range of from 0.001 to 30% by weight relative to the total weight of the preparation.
4. Preparation according to claim 1 , comprising at least one further UV filter substance comprising at least one of triazines, benzotriazoles, liquid UV filter substances and at least one of organic and inorganic pigments.
5. Preparation according to claim 1 , comprising at least one further UVA filter substance and/or a broadband filter comprising at least one of dibenzoylmethane derivatives and 2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxy]phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine.
6. Preparation according to claim 1 , comprising at least one of at least one flavone glycoside and vitamin E and/or derivatives thereof.
7. A method of moistening skin comprising applying a preparation according to claim 1 on the skin.
8. A method of protecting skin against light-related aging of the skin comprising applying a preparation according to claim 1 on the skin.
9. A method of achieving or increasing solubility of at least one hydroxybenzophenone comprising combining said at least one hydroxybenzophenone, the at least one hydroxybenzophenone having the following structural formula:
where
R 1 and R 2 independent of one another are hydrogen, C 1 –C 20 -alkyl, C 3 –C 10 - cycloalkyl or C 3 –C 10 -cyloalkenyl, wherein the substituents R 1 and R 2 together with the nitrogen atom to which they are bound can form a 5- or 6-ring, and
R 3 is a C 1 –C 20 alkyl radical, and
with at least one dialkyl naphthalate comprising the structural formula
where R 1 and R 2 are independently one of branched and unbranched alkyl groups with 6 to 24 carbon atoms.
10. A method of stabilizing dibenzoylmethane derivatives in cosmetic or dermatological preparations against decomposition that is induced by UV radiation comprising including combinations of
(a) at least one hydroxybenzophenone of the following structural formula:
where
R 1 and R 2 independent of one another are hydrogen, C 1 –C 20 -alkyl, C 3 –C 10 -cycloalkyl or C 3 –C 10 -cyloalkenyl, wherein the substituents R 1 and R 2 , together with the nitrogen atom to which they are bound can form a 5- or 6-ring, and
R 3 is a C 1 –C 20 alkyl radical, and
(b) at least one dialkyl naphthalate of the structural formula
where R 1 and R 2 are independently one of branched and unbranched alkyl groups with 6 to 24 carbon atoms, in a cosmetic or dermatological preparation containing dibenzoylmethane derivatives in an amount effective to stabilize the dibenzoylmethane derivatives against the decomposition that is induced by UV radiation.
11. Preparation according to claim 3 , wherein the at least one dialkyl naphthalate is present in a range of from 0.01 to 20% by weight relative to the total weight of the preparation.
12. Preparation according to claim 11 , wherein the at least one dialkyl naphthalate is present in a range of from 0.5 to 15% by weight relative to the total weight of the preparation.
13. Preparation according to claim 5 , wherein said dibenzoylmethane derivatives comprise 4-(tert-butyl)-4′- methoxydibenzoylmethane].
14. Preparation according to claim 1 , wherein the at least one flavone glycoside comprises α-glucosylrutin.
15. Preparation according to claim 2 , wherein the at least one dialkyl naphthalate is present in a range of from 0.001 to 30% by weight-relative to the total weight of the preparation.
16. Preparation according to claim 2 , comprising at least one further UV filter substance comprising at least one of triazines, benzotriazoles, liquid UV filter substances and at least one of organic and inorganic pigments.
17. Preparation according to claim 2 , comprising at least one further UVA filter substance and/or a broadband filter comprising at least one of dibenzoylmethane derivatives and 2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxy]phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine.
18. Preparation according to claim 2 , comprising at least one of at least one flavone glycoside and vitamin E and/or derivatives thereof.
19. Preparation according to claim 5 , comprising at least one further UVA filter substance and/or a broadband filter comprising at least one of dibenzoylmethane derivatives and 2,4-bis{[4-(2-ethylhexyloxy)-2-hydroxy]phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine.
20. Preparation according to claim 4 , comprising at least one of at least one flavone glycoside and vitamin E and/or derivatives thereof.