Granted Patent
B2
US 7,208,576 · App. 10/624,380 · Granted Apr 24, 2007
Non-glycosylated human alpha-fetoprotein, methods of production, and uses thereof
Assignee:
Merrimack Pharmaceuticals, Inc.
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Abstract
The invention features non-glycosylated human alpha-fetoprotein, methods of production, and uses thereof.
Claims (3)
1. Non-glycosylated HuAFP (ng.HuAFP) comprising a glutamine residue at position 233 of SEQ ID NO: 4.
2. A polypeptide comprising the amino acid sequence set forth in SEQ ID NO: 6, wherein said polypeptide comprises a glutamine residue at position 251.
3. A substantially pure biologically-active fragment of non-glycosylated human alpha-fetoprotein, wherein said fragment comprises the amino acid sequence set forth in SEQ ID NO: 15 (Domain II), SEQ ID NO: 16 (Domain I+II), or SEQ ID NO: 17 (Domain I+III), or two or more of said amino acid sequences.
Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 4, 2017
From: MERRIMACK PHARMACEUTICALS, INC.
To: ALPHA CANCER TECHNOLOGIES INC.
Reel/Frame 043209/0196 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 18, 2003
From: GTC BIOTHERAPEUTICS, INC.
To: MERRIMACK PHARMACEUTICALS, INC.
Reel/Frame 014387/0512 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 18, 2003
From: MULROY, ROBERT
To: MERRIMACK PHARMACEUTICALS, INC.
Reel/Frame 014387/0524 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 18, 2003
From: KRANE, IAN
To: GTC BIOTHERAPEUTICS INC
Reel/Frame 014387/0591 →
Continuity (1)