Crystalline parahydroxybenzoic acid anhydride and process for preparing the same
View Patent ↗The present invention provides a process for preparing crystalline parahydroxybenzoic acid anhydride, comprising the step of precipitating and isolating parahydroxybenzoic acid in an aqueous solvent at a temperature equal to or above the transition temperature of parahydroxybenzoic acid.
1. A process for preparing crystalline parahydroxybenzoic acid anhydride, comprising the step of precipitating and isolating parahydroxybenzoic acid in an aqueous solvent at a temperature equal to or above the transition temperature of parahydroxybenzoic acid.
2. The process for preparing crystalline parahydroxybenzoic acid anhydride according to claim 1 , wherein the precipitating and isolating step is performed at a temperature which is in the range from the transition temperature to the transition temperature +30° C.
3. A process for preparing crystalline parahydroxybenzoic acid anhydride, comprising the step of precipitating and isolating parahydroxybenzoic acid with acid from a solution of parahydroxybenzoate in an aqueous solvent at a temperature equal to or above the transition temperature of parahydroxybenzoic acid.
4. A process for preparing crystalline parahydroxybenzoic acid anhydride, comprising the steps of: precipitating parahydroxybenzoic acid in an aqueous solvent with acid, heating the parahydroxybenzoic acid precipitates to dissolve the same, and re-precipitating and isolating the parahydroxybenzoic acid at a temperature equal to or above the transition temperature of parahydroxybenzoic acid.
5. A process for preparing crystalline parahydroxybenzoic acid anhydride, comprising the steps of:
providing;
a liquid solution of parahydroxybenzoic acid in an aqueous solvent by heating a suspension of parahydroxybenzoic acid monohydride in an aqueous solvent:
precipitating crystalline parahydroxybenzoic acid anhydride by keeping said solution at a temperature equal to or above the transition temperature of parahydroxybenzoic acid; and
isolating the crystalline parahydroxybenzoic acid anhydride at a temperature equal to or above the transition temperature of parahydroxybenzoic acid.
6. A process for preparing crystalline parahydroxybenzoic acid anhydride, comprising the steps of:
provide a suspension of parahydroxybenzoic acid monohydride in an aqueous solvent,
converting parahydroxybenzoic acid monohydride to parahydroxybenzoic acid anhydride by heating the suspension to a temperature equal to or above the transition temperature of parahydroxybenzoic acid, and
isolating the crystalline parahydroxybenzoic acid anhydride at a tempertaure equal to or above the transition temperature of parahydroxybenzoic acid.
7. The process for preparing crystalline parahydroxybenzoic acid anhydride according to claim 1 , 2 , 3 , 4 , 5 or 6 , wherein the aqueous solvent is water and the transition temperature of parahydroxybenzoic acid is 52 to 54° C.
8. Crystalline parahydroxybenzoic acid anhydride prepared by the method of claim 1 , wherein particles of parahydroxvbenzoic acid anhydride can pass through a 100 mesh (150 μm) sieve and can not pass through a 140 mesh (106 μm) sieve, and the specific surface area of the particles is equal to or less than 0.3 m2/g.
9. The crystalline parahydroxybenzoic acid anhydride according to claim 8 , wherein the angle of repose is equal to or less than 45°.
10. The crystalline parahydroxybenzoic acid anhydride according to claim 8 or 9 , wherein the compression ratio calculated according to the following formula is equal to or less than 10%: (packed bulk density-aerated bulk density)/packed bulk density×100.