IP Library Granted Patent US 7,416,722
Granted Patent B2
US 7,416,722 · App. 11/396,856 · Granted Aug 26, 2008

Concentrated, aqueous solutions of p-methoxybenzoic acid for use in cosmetic and dermatologic formulations

Assignee: Dr. Straetmans GmbH
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Quick Facts
Patent No.
US 7,416,722
App. No.
11/396,856
Granted
Aug 26, 2008
Kind
B2
Abstract

The present invention is related to concentrated aqueous solutions of p-methoxybenzoic acid and their production.

Claims (119)

1. A liquid, composition comprising:

a) 5-15 weight % p-methoxybenzoic acid, or salt thereof:

b) 5-60 weight % of water; and

at least one of c) and/or d):

c) 20-55 weight % one or more of an organic acid and/or their salts;

d) 20-60 weight % one or more of a polyol, an ester of polyglycerol and an ester of sorbitan; said composition having a pH of 7.0-8.0.

2. The composition of claim 1 comprising:

a) 5 weight % to 10 weight % sodium salts of p-methoxybenzoic acid;

b) 5 weight % to 55 weight % water;

c) 20 weight % to 30 weight % sodium levulinate

d) 20 weight % to 55 weight % glycerol.

3. A method of producing a composition comprising

a) 5 weight % to 10 weight % sodium salts of p-methoxybenzoic acid;

b) 5 weight % to 55 weight % water;

c) 20 weight % to 30 weight % sodium levulinate

d) 20 weight % to 55 weight % glycerol; the method comprising dispersing p-methoxybenzoic acid in glycerol, subsequently adding an amount of aqueous sodium hydroxide which is equimolar to the calculated total amount of acids, adjusting the pH-value to 7.0-8.0 with levulinic acid and adding the remaining water.

4. The composition of claim 1 wherein component c) comprises a sodium salt of levulinic acid, a potassium salt of levulinic acid, a sodium salt of lactic acid, a potassium salt of lactic acid, a sodium salt of citric acid, a potassium salt of citric acid, or an ammonium salts of the formula HNR 3 + , wherein R═H, alkyl, hydroxyalkyl.

5. The composition of claim 1 wherein component d) comprises a glycol, a glycerol, or an ester of sorbitan.

6. The composition of claim 1 wherein component d) comprises propylene glycol, butylene glycol, dipropylene glycol, 2-methylpropanediol, polyglyceryl-10 laurate, or sorbitan laurate.

7. The composition of claim 1 wherein component c) comprises a sodium salt of levulinic acid, a potassium salt of levulinic acid, a sodium salt of lactic acid, a potassium salt of lactic acid, a sodium salt of citric acid, a potassium salt of citric acid, or an ammonium salts of the formula HNR 3 + , wherein R═H, alkyl, hydroxyalkyl; and wherein component d) comprises propylene glycol, butylene glycol, dipropylene glycol, 2-methylpropanediol, polyglyceryl-10 laurate, or sorbitan laurate.

8. The composition of claim 1 comprising:

 5 g

p-methoxybenzoic acid

 30 g

glycerol

15.0 g 

10% sodium hydroxide in water

100 g

water.

9. The composition of claim 1 comprising:

  5 g

p-methoxybenzoic acid

31.5 g

polyglyceryl-10 laurate

14.0 g

10% sodium hydroxide in water

 100 g

water

said composition having a pH = 7.5.

10. The composition of claim 1 comprising:

 5 g

p-methoxybenzoic acid

21 g

levulinic acid

19 g

45% aqueous sodium hydroxide

50 g

glycerol

100 g 

water

said composition having a pH = 7.5.

11. The composition of claim 1 comprising:

 7.5 g

p-methoxybenzoic acid

22.5 g

levulinic acid

21.5 g

45% aqueous sodium hydroxide

  25 g

glycerol

 100 g

water

said composition having a pH = 7.5.

12. A perfume, masking agent, aromatizing, cosmetic or dermatologic formulation which comprises a liquid, composition comprising:

a 5-15 weight % p-methoxybenzoic acid, or salt thereof;

b) 5-60 weight % of water; and at least one of c) and/or d):

c) 20-55 weight % one or more of an organic acid and/or their salts;

d) 20-60 weight % one or more of a polyol, an ester of polyglycerol and an ester of sorbitan; said composition having a pH of 7.0-8.0.

13. The formulation of claim 12 wherein the liquid, composition comprises:

a) 5 weight % to 10 weight % sodium salts of p-methoxybenzoic acid;

b) 5 weight % to 55 weight % water;

c) 20 weight % to 30 weight % sodium levulinate

d) 20 weight % to 55 weight % glycerol.

14. The formulation of claim 12 wherein component c) comprises a sodium salt of levulinic acid, a potassium salt of levulinic acid, a sodium salt of lactic acid, a potassium salt of lactic acid, a sodium salt of citric acid, a potassium salt of citric acid, or an ammonium salts of the formula HNR 3 30 , wherein R═H, alkyl, hydroxyalkyl.

15. The formulation of claim 12 wherein component d) comprises a glycol, a glycerol, or an ester of sorbitan.

16. The formulation of claim 12 wherein component d) comprises propylene glycol, butylene glycol, dipropylene glycol, 2-methylpropanediol, polyglyceryl-10 laurate, or sorbitan laurate.

17. The formulation of claim 12 wherein the liquid, composition comprises:

 5 g

p-methoxybenzoic acid

 30 g

glycerol

15.0 g 

10% sodium hydroxide in water

100 g

water.

18. The formulation of claim 12 wherein the liquid, composition comprises:

  5 g

p-methoxybenzoic acid

31.5 g

polyglyceryl-10 laurate

14.0 g

10% sodium hydroxide in water

 100 g

water

said composition having a pH = 7.5.

19. The formulation of claim 12 wherein the liquid, composition comprises:

 5 g

p-methoxybenzoic acid

21 g

levulinic acid

19 g

45% aqueous sodium hydroxide

50 g

glycerol

100 g 

water

said composition having a pH = 7.5.

20. The formulation of claim 12 wherein the liquid, composition comprises:

 7.5 g

p-methoxybenzoic acid

22.5 g

levulinic acid

21.5 g

45% aqueous sodium hydroxide

  25 g

glycerol

 100 g

water

said composition having a pH = 7.5.

Assignments (3)
CHANGE OF NAME Recorded Mar 30, 2020
From: EVONIK DEGUSSA GMBH
To: EVONIK OPERATIONS GMBH
Reel/Frame 052267/0790 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 2, 2018
From: DR. STRAETMANS GMBH
To: EVONIK DEGUSSA GMBH
Reel/Frame 044810/0893 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 3, 2006
From: STRAETMANS, UDO; JANICHEN, JAN; PETERSEN, WILFRIED; KINDER, MICHAEL; JOHNSON, CHRISTOHER H.; REYNOLDS, GARRETT S.
To: DR. STRAETMANS GMBH
Reel/Frame 017750/0397 →
Priority Claims (1)
EP 05007721 · Apr 8, 2005 · regional
Continuity (1)
Related Publication 20060229291A1 · Oct 12, 2006