IP Library Granted Patent US 7,436,175
Granted Patent B2
US 7,436,175 · App. 10/538,361 · Granted Oct 14, 2008

Practical pulse synthesis via the discrete inverse scattering transform

Assignee: The Trustees of The University of Pennsylvania
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Quick Facts
Patent No.
US 7,436,175
App. No.
10/538,361
Granted
Oct 14, 2008
Kind
B2
Abstract

The discrete inverse scattering (DIST) approach is used to design selective RF pulses. As in SLR, a hard pulse approximation is used to actually design the pulse. Unlike SLR, the pulse is designed using the full inverse scattering data (the reflection coefficient and the bound states) rather than the flip angle profile. The reflection coefficient is approximated in order to obtain a pulse with a prescribed rephasing time. In contrast to the SLR approach, direct control on the phase of the magnetization profile is retained throughout the design process. Explicit recursive algorithms are provided for computing the hard pulse from the inverse scattering data. These algorithms are essentially discretizations of the Marchenko equations. When bound states are present, both the left and right Marchenko equations are used in order to improve the numerical stability of the algorithm. The DIST algorithm is used in preferred applications to generate pulses for use in magnetic resonance imaging, although it has applications in other two-level quantum systems such as quantum computing and spintronics.

Claims (13)

1. A method of generating a desired frequency dependent excitation in a system including at least one of a two-level quantum system and a subsystem described by the spin domain Bloch equation using selective pulses for a given selective excitation profile corresponding to said desired frequency dependent excitation, comprising the steps of:

determining frequency envelopes to produce the given selective excitation profile;

producing a plurality of solutions via an inverse scattering transform producing said envelopes, including identifying and producing a minimum energy solution to said inverse scattering transform for pulses that generate the given selective excitation profile;

generating pulses corresponding to any of the plurality of solutions to produce the envelopes that produce said given selective excitation profile;

applying the generated pulses to said system to obtain said desired frequency dependent excitation; and

obtaining the system's response to said desired frequency dependent excitation.

2. A method as in claim 1 , wherein said system includes one of a quantum computer system and a spintronics system.

3. A method as in claim 1 , wherein said system is a magnetic resonance imaging system, said pulses comprise radiofrequency (RF) pulses, said frequency envelopes comprises RF envelopes, and said selective excitation profile comprises an arbitrary magnetization profile.

4. A method as in claim 3 , wherein said arbitrary magnetization profile is an arbitrary unit 3 vector valued function of a single real variable.

5. The method of claim 3 , wherein said solutions producing step comprises the step of using a reflection coefficient corresponding to a hard pulse approximation to approximate an ideal reflection coefficient that is determined by said given magnetization profile.

6. The method of claim 1 , wherein said solutions producing step comprises the step of specifying bound states and norming constants for reduced scattering data subject to constraints on the energy to be used in said inverse scattering transform.

7. The method of claim 1 , comprising the additional step of increasing the energy of a frequency envelope in order to reduce rephasing time while maintaining a constraint on the energy to be used in said inverse scattering transform.

8. The method of claim 1 , wherein said applying step comprises the steps of generating a softened pulse approximation to said envelopes from the pulses generated in said generating step and applying said softened pulse approximation to said system.

Assignments (2)
CONFIRMATORY LICENSE Recorded Aug 31, 2018
From: UNIVERSITY OF PENNSYLVANIA
To: NATIONAL SCIENCE FOUNDATION
Reel/Frame 046993/0227 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 20, 2005
From: EPSTEIN, CHARLES L.; MAGLAND, JEREMY
To: TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THE
Reel/Frame 016918/0479 →
Continuity (2)
Provisional Application 6043340700 · Dec 13, 2002
Related Publication 20060113994A1 · Jun 1, 2006