Spider silk protein encoding nucleic acids, polypeptides, antibodies and methods of use thereof
Spider silk protein encoding nucleic acids, polypeptides and antibodies immunologically specific therefore are disclosed. Methods of use thereof are also provided.
1. An isolated nucleic acid molecule selected from the group consisting of a nucleic acid sequence encoding a protein of SEQ ID NOS: 36-44.
2. An isolated nucleic acid encoding an MaSP2-like spider silk protein having a plurality of repeating GPG(X)n and An units and a sequence having at least 90% identity to a sequence selected from the group consisting of SEQ ID NOS: 36-44.
3. An isolated nucleic acid encoding SEQ ID NO: 36 as claimed in claim 2 .
4. An isolated nucleic acid encoding SEQ ID NO: 37 as claimed in claim 2 .
5. An isolated nucleic acid encoding SEQ ID NO: 38 as claimed in claim 2 .
6. An isolated nucleic acid encoding SEQ ID NO: 39 as claimed in claim 2 .
7. An isolated nucleic acid encoding SEQ ID NO: 40 as claimed in claim 2 .
8. An isolated nucleic acid encoding SEQ ID NO: 41 as claimed in claim 2 .
9. An isolated nucleic acid encoding SEQ ID NO: 42 as claimed in claim 2 .
10. An isolated nucleic acid encoding SEQ ID NO: 43 as claimed in claim 2 .
11. An isolated nucleic acid encoding SEQ ID NO: 44 as claimed in claim 2 .
12. An expression vector comprising at least one of the nucleic acids of claim 2 .
13. A host cell comprising the expression vector of claim 12 .
14. An isolated spider silk protein comprising a sequence selected from the group consisting of SEQ ID NOS: 36-44.
15. A silk fiber comprising at least one of the proteins of claim 14 .
16. A copolymer fiber comprising at least two of the proteins of claim 14 .