IP Library › Granted Patent US 7,569,683
Granted Patent B2
US 7,569,683 · App. 12/044,818 · Granted Aug 4, 2009

UspA2 nucleic acid of

Assignees: Board of Regents, The University of Texas System; Wyeth Holding Corporation
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Quick Facts
Patent No.
US 7,569,683
App. No.
12/044,818
Granted
Aug 4, 2009
Kind
B2
Abstract

The present invention discloses the existence of two novel proteins UspA1 and UspA2, and their respective genes uspA1 and uspA2. Each protein encompasses a region that is conserved between the two proteins and comprises an epitope that is recognized by the MAb 17C7. One or more than one of these species may aggregate to form the very high molecular weight form (i.e. greater than 200 kDa) of the UspA antigen. Compositions and both diagnostic and therapeutic methods for the treatment and study of M. catarrhalis are disclosed.

Claims (2)

1. An isolated nucleic acid encoding the UspA2 antigen (SEQ ID NO:15) of the M. catarrhalis isolate TTA37.

2. An isolated nucleic acid having the uspA2 DNA sequence (SEQ ID NO:16) of the M. catarrhalis isolate TTA37.

Assignments (1)
CONFIRMATORY LICENSE Recorded Dec 16, 2009
From: THE UNIVERSITY OF TEXAS SYSTEM
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 023659/0077 →
Continuity (5)
Division 1087276900 · Jun 21, 2004
Division 0933644700 · Jun 21, 1999
Continuation PCTUS972393000 · Dec 19, 1997
Provisional Application 6003359800 · Dec 20, 1996
Related Publication 20090137788A1 · May 28, 2009