Dermatological composition
Dermatological compositions containing a humectant, e.g., at least one of urea, ammonium lactate, and glycerin, and an emollient, e.g., at least one of Shea or cocoa butter, glycine soja sterol and hybrid sunflower oil. The compositions of the invention may be utilized for treatment or amelioration of skin disorders or adverse physiological conditions, and such compositions may be employed as a base for cosmetic or pharmaceutical formulations for dermal administration.
1. A dermatological composition consisting of water and the following ingredients in the following percentages by weight, based on total weight of the composition: urea in an amount of 1-50% by weight; disodium EDTA in an amount of 0.05-0.3% by weight; sodium polyacrylate in an amount of 0.1-1.5% by weight; stearic acid in an amount of 3.0-8.0% by weight; glyceryl stearate in an amount of 2.0-10.0% by weight; soybean sterol in an amount of 1.0-4.0% by weight; shea butter in an amount of 0.5-10% by weight; sunflower oil in an amount of 2.0-15% by weight; butylated hydroxytoluene in an amount of 0.05-0.5% by weight; and triethanolamine in an amount of 0.25-2.5% by weight, wherein weight percentages of all ingredients total to 100 weight percent.
2. The dermatological composition of claim 1 , wherein the amount of urea in the composition is from 20% to 50% by weight, based on the total weight of the composition.
3. The dermatological composition of claim 1 , wherein the amount of urea in the composition is from 20 to 41%.
4. The dermatological composition of claim 1 , wherein the amount of urea in the composition is 40%.
5. A dermatological formulation, consisting of:
a base composition; and
a therapeutic agent selected from the group consisting of: wound healing agents, anti-inflammatory agents, glucocorticosteroids, hydrocortisone, triamcinolone, betametamethasone, ibuprofen, ketoprofen, methyl salicylate, anti-infective agents, bacitracin, polymixin B, mupirocin, neomycin, enzymes, anti-fungal agents, anti-viral agents, acne-combating agents, rosacea-combating agents, dermatitis-combating agents, and topical immunomodulator agents,
wherein the base composition consists of water and the following ingredients in the following percentages by weight, based on total weight of the composition: urea in an amount of 1-50% by weight; disodium EDTA in an amount of 0.05-0.3% by weight; sodium polyacrylate in an amount of 0.1-1.5% by weight; stearic acid in an amount of 3.0-8.0% by weight; glyceryl stearate in an amount of 2.0-10.0% by weight; soybean sterol in an amount of 1.0-4.0% by weight; shea butter in an amount of 0.5-10% by weight; sunflower oil in an amount of 2.0-15% by weight; butylated hydroxytoluene in an amount of 0.05-0.5% by weight; and triethanolamine in an amount of 0.25-2.5% by weight, wherein weight percentages of all ingredients total to 100 weight percent.