Granted Patent
B2
US 7,589,173 · App. 10/781,564 · Granted Sep 15, 2009
Methods for diagnosing cancer and decreasing metastasis by cancer cells
Assignee:
The Scripps Research Institute
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Abstract
The invention provides a protein that is a tumor marker protein. This protein can be used to prepare antibodies that bind to the tumor marker protein. These antibodies can be used to reduce, or eliminate metastasis by cancer cells that produce the tumor marker protein. In addition, the invention provides methods that can be used to diagnose cancer, and metastasis by cancer cells.
Claims (3)
1. An isolated protein having SEQ ID NO: 1 that is glycosylated.
2. An isolated variant of SEQ ID NO: 1, wherein the variant results from the substitution of the glutamine with an arginine at amino acid 525.
3. An isolated variant of SEQ ID NO: 1, wherein the variant results from the substitution of the asparagine with a serine at amino acid 827.
Assignments (2)
CONFIRMATORY LICENSE
Recorded Dec 19, 2017
From: THE SCRIPPS RESEARCH INSTITUTE
To: NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR
Reel/Frame 044440/0771 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jul 26, 2004
From: QUIGLEY, JAMES P.; HOOPER, JOHN D.; TESTA, JACQUELINE E.
To: SCRIPPS RESEARCH INSTITUTE, THE
Reel/Frame 014896/0102 →
Continuity (2)
Provisional Application
6044882800
· Feb 19, 2003