Compositions and methods for treatment of candidiasis

1. A method of reducing the risk of or therapeutic treatment of a condition caused by Candida albicans colonization or infection, comprising administering to a subject requiring such treatment a therapeutically effective amount of a composition formulated for oral administration or subcutaneous injection comprising inactivated blastospores of Candida albicans.

2. The method according to claim 1 , wherein the condition is mucositis.

3. The method according to claim 1 , wherein the condition is selected from the group consisting of recurrent/persistent stomatitis, recurrent vulvovaginal candidiasis, oesophagitis and lower urinary tract or bowel colonisation.

4. The method according to claim 1 , further comprising the administration of an adjuvant before, during, or after cessation of treatment.

5. The method according to claim 4 , wherein the adjuvant is administered orally.

6. The method according to claim 4 , wherein the adjuvant is administered subcutaneously.

7. The method according to claim 1 , wherein the condition is selected from the group consisting of oral, nasopharyngeal and respiratory tract colonization.

8. The method according to claim 1 , wherein the condition is oral colonization.

9. The method according to claim 1 , further comprising administration of the probiotic before, during, or after cessation of treatment.

10. A method of reducing the risk of or therapeutic treatment of a condition caused by Candida albicans colonization or infection, comprising administering to a subject requiring such treatment a therapeutically effective amount of a composition formulated for oral administration comprising inactivated blastospores of Candida albicans and a probiotic.

11. The method of claim 9 or 10 , wherein the probiotic is a probiotic bacterium.

12. The method of claim 11 , wherein the probiotic bacterium is a lactic acid bacterium.

13. The method according to claim 12 , wherein the lactic acid bacterium is Lactobaccillus acidophilus.