Automated system of processing biological specimens and method
An automated laboratory slide management and interpretation system and method in which slides are stained and then digitally imaged and the images are interpreted prior to referral to a diagnostician or placement in storage. The interpretation of the images involves the application of pattern recognition principles to compare the digitized images to known sample patterns from a variety of sources. Additionally, based on the results of the interpretation, the slide may undergo additional testing or staining, and additional samples may be prepared and tested. The specimens may be delivered to the diagnostician along with a tentative diagnosis.
1. A system of processing biological specimens, comprising:
a biological material handling system;
a communication infrastructure in communication with the material handling system;
a slide processing module including at least one of a staining module and a testing module;
a slide imaging module in communication with the communication infrastructure and generating slide image data; and
an interpretation module in communication with the slide imaging module utilizing pattern recognition technology to compare the slide image data to reference image data in order to generate an initial interpretation of the image data, the interpretation module communicating with the material handling system and the slide processing module to return the slide to the slide processing module and obtain additional staining or testing in accordance with the initial interpretation of the image data,
wherein the staining module, the slide imaging module and the interpretation module are implemented as a single automated instrument.
2. The system of processing biological specimens of claim 1 , further comprising a determination module generating staining instruction data for carrying out at least one staining procedure in the staining module in accordance with said staining instruction data.
3. The system of processing biological specimens of claim 2 , further comprising: a sectioning device; and a sectioning instruction receiving module.
4. The system of processing biological specimens of claim 3 , further comprising a coverslipper module.
5. The system of processing biological specimens of claim 1 wherein the interpretation module is in communication with the slide imaging module via the communications infrastructure.
6. The system of processing biological specimens of claim 1 wherein the interpretation module is in communication with the slide imaging module via a direct data path.
7. A system of processing biological specimens, comprising:
a biological material handling system;
a communication infrastructure in communication with the material handling system; a slide preparation module;
a slide imaging module in communication with the communication infrastructure and generating slide image data for a slide under test; and
an interpretation module in communication with the slide imaging module utilizing pattern recognition technology to compare the slide image data to reference image data in order to generate an initial interpretation of the image data, the interpretation module communicating with the material handling system and the slide preparation module to prepare and image an additional slide in response to the initial interpretation of the image data,
wherein the staining module, the slide imaging module and the interpretation module are implemented as a single automated instrument.
8. The system of processing biological specimens of claim 7 , further comprising a determination module generating staining instruction data for carrying out at least one staining procedure in the staining module in accordance with said staining instruction data.
9. The system of processing biological specimens of claim 8 , further comprising: a sectioning device; and a sectioning instruction receiving module.
10. The system of processing biological specimens of claim 9 , further comprising a coverslipper module.
11. The system of processing biological specimens of claim 7 wherein the interpretation module is in communication with the slide imaging module via the communications infrastructure.
12. The system of processing biological specimens of claim 7 wherein the interpretation module is in communication with the slide imaging module via a direct data path.
13. The system of processing biological specimens of claim 7 wherein the additional slide is at least partially prepared concurrently with the slide under test.