Granted Patent
B2
US 7,666,881 · App. 11/534,828 · Granted Feb 23, 2010
Methods of treating allergic reactions using hydrated forms of antihistaminic piperidine derivatives
Assignee:
Aventis Holdings, Inc.
View Patent ↗
Loading inventors, assignments & file history…
Abstract
The present invention is related to novel processes for preparing anhydrous and hydrated forms of piperidine derivatives, polymorphs and pseudomorphs thereof of the formulas which are useful as antihistamines, antiallergic agents and bronchodilators.
Claims (1)
1. A method of treating an allergic reaction in a patient in need thereof comprising administering to said patient a solid unit dosage form comprising an effective amount of 4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylbenzeneacetic acid hydrochloride comprising Form II hydrated 4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylbenzeneacetic acid hydrochloride.
Assignments (7)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Mar 2, 2010
From: AVENTIS HOLDINGS INC.
To: AVENTISUB II INC.
Reel/Frame 024006/0487 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 20, 2009
From: HENTON, DANIEL R.
To: THE DOW CHEMICAL COMPANY
Reel/Frame 023121/0056 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 19, 2009
From: THE DOW CHEMICAL COMPANY
To: HOECHST MARION ROUSSEL, INC.
Reel/Frame 023116/0799 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 19, 2009
From: AVENTIS PHARMACEUTICALS INC.
To: HMR PHARMA INC.
Reel/Frame 023117/0072 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 19, 2009
From: HMR PHARMA INC.
To: AVENTIS HOLDINGS INC.
Reel/Frame 023117/0088 →
CHANGE OF NAME
Recorded Aug 19, 2009
From: HOECHST MARION ROUSSEL, INC.
To: AVENTIS PHARMACEUTICALS INC.
Reel/Frame 023117/0056 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 19, 2009
From: PETERSON, SCOTT E.; STRENG, WILLIAM H.; MCCARTY, FREDERICK J.; TRIPP, SUSAN I.; DEWITT, JILL E.
To: HOECHST MARION ROUSSEL, INC.
Reel/Frame 023116/0604 →
Continuity (8)