Method of fabricating a stent with features by blow molding

1. A method of manufacturing a stent, the method comprising:

disposing a polymeric tube into a cylindrical mold, the cylindrical mold having a protrusion or indentation on the inside surface of the mold;

radially expanding the tube by blowing a gas or liquid into the cylindrical mold, the outside surface of the tube conforming to protrusion or indentation on the inside surface of the mold, the protrusion in the mold causing an indentation on the outside surface of the tube, or the indentation in the mold causing a protrusion on the outside surface of the tube; and

fabricating a stent with the expanded tube, wherein the fabricating comprises laser cutting a pattern having the indentation or protrusion on the surface of a strut.

2. The method according to claim 1 , wherein the thickness at the protrusion on the expanded tube is greater than other portions of the expanded tube.

3. The method according to claim 1 , wherein the thickness at the indentation on the expanded tube is less than other portions of the expanded tube.

4. A method of manufacturing a stent, the method comprising:

disposing a polymeric tube into a cylindrical mold, the cylindrical mold having a protrusion or indentation on the inside surface of the mold;

radially expanding the tube by blowing a gas or liquid into the cylindrical mold, the outside surface of the tube conforming to protrusion or indentation on the inside surface of the mold, the protrusion in the mold causing an indentation on the outside surface of the tube, or the indentation in the mold causing a protrusion on the outside surface of the tube; and

fabricating a stent with the expanded tube, wherein the stent is fabricated so that bending portions are located in thicker portions of the stent.

5. The method according to claim 1 , wherein the indentation comprises a groove.

6. The method according to claim 1 , wherein the tube comprises a biodegradable and/or biostable polymer.

7. The method according to claim 1 , further comprising heating the tube with the liquid or gas to a temperature above Tg of the polymer before and/or during expansion.

8. A method of manufacturing a stent, the method comprising:

disposing a polymeric tube into a cylindrical mold, the cylindrical mold having an indentation or a protrusion on the inside surface of the mold;

radially expanding the tube by blowing a gas or liquid into the cylindrical mold, the outside surface of the tube conforming to the indentation or protrusion of the inside surface of the mold, the indentation or protrusion on the mold causing a feature on the outside surface of the tube; and

fabricating a stent with the expanded tube, wherein the fabricating comprises cutting a pattern having the indentation or protrusion on the surface of a strut.

9. The method according to claim 8 , wherein the feature formed on the outside surface of the tube is an indentation, and the method further comprises filling the indentation with a radio-opaque material.

10. The method according to claim 8 , wherein the feature formed on the outside surface of the tube is an indentation, and the method further comprises filling the indentation with a drug.

11. The method according to claim 8 , wherein the cylindrical mold has both an indentation and a protrusion on the inside surface, thereby forming both a protrusion and an indentation on the outside surface of the tube.

12. The method according to claim 1 , wherein the stent is fabricated so that bending portions are located in thicker portions of the stent.

13. The method according to claim 4 , wherein the fabricating comprises cutting a pattern having the indentation or protrusion on the surface of a strut.

14. The method according to claim 8 , wherein the stent is fabricated so that bending portions are located in thicker portions of the stent.