Method for treatment of premature ejaculation in humans
The present invention belongs to the fields of pharmacology, medicine and medicinal chemistry, and provides methods and compositions for treating sexual dysfunction; more particularly, the invention relates to treatment of premature ejaculation in humans.
1. A method for delaying the onset of ejaculation in a male individual, comprising administering to the individual a pharmaceutical formulation consisting essentially of dextromethorphan, sildenafil, and acetaminophen in an amount effective to delay the onset of ejaculation by the individual during sexual intercourse, wherein said administration is oral, parenteral or by intracavernosal injection.
2. The method of claim 1 , wherein said administration is parenteral.
3. The method of claim 1 , wherein said administration is by intracavernosal injection.
4. A method for delaying the onset of ejaculation in a male individual who has a premature ejaculation problem, comprising administering to the individual a pharmaceutical formulation consisting essentially of a combination of sildenafil, dextromethorphan, and acetaminophen in an amount effective to delay the onset of ejaculation by the individual during sexual intercourse, wherein the formulation is administered orally, parenterally or by intracavernosal injection.
5. The method of claim 4 , wherein the formulation is administered parenterally.
6. The method of claim 4 , wherein the formulation is administered by intracavernosal injection.
7. The method of claim 4 , wherein the sildenafil, dextromethorphan, and acetaminophen are administered combined in a single dosage form.
8. The method of claim 1 , wherein the pharmaceutical formulation consists of dextromethorphan, sildenafil and acetaminophen in an amount effective to delay the onset of ejaculation by the individual during sexual intercourse, and a pharmaceutically acceptable carrier or excipient.
9. The method of claim 4 , wherein the pharmaceutical formulation consists of dextromethorphan, sildenafil and acetaminophen in an amount effective to delay the onset of ejaculation by the individual during sexual intercourse, and a pharmaceutically acceptable carrier or excipient.