Method of fabricating an integrated intraocular retinal prosthesis device
View Patent ↗Intraocular retinal prosthesis devices and methods for fabricating the same. A prosthesis device includes a cable region that connects an electrode array region with a power and data management region. The electrode array region includes one or more arrays of exposed electrodes, and the power and data management region includes various power and control elements. The power and data management elements, in one aspect, include an RF coil or coils and circuit arrangements and/or chips configured to provide drive signals to the electrodes via a cable and receive power and signals from the RF coil or coils. Each region includes elements fabricated on or in a single polymer layer during the same fabrication process.
1. A method of fabricating an integrated intraocular retinal prosthesis device having an electrode array region, a power and data management region and a cable region connecting the electrode region with the power and data management region, the method comprising:
forming a patterned layer of conductive material on a first layer of polymer material, said patterned conductive layer defining circuit elements of the power and data management region, the electrode region and the cable region wherein the circuit elements of the power and data management region include one or more RF coil elements formed of the conductive material;
covering the patterned conductive layer with a second polymer layer; and
removing a portion of the second polymer layer in the electrode array region so as to expose at least a portion of the patterned conductive layer to form an exposed electrode array.
2. The method of claim 1 , wherein the conductive material comprises carbonized parylene.
3. The method of claim 1 , wherein the conductive material comprises a conductive metal selected from the group consisting of gold, platinum, chromium, titanium, platinum and iridium oxide.
4. The method of claim 1 , wherein the first polymer layer and the second polymer layer each comprise one or more of parylene A, parylene C, parylene AM, parylene F, parylene N, parylene HT or parylene D.
5. The method of claim 1 , wherein the device includes one or more retention elements configured to retain the RF coil elements in an implant region of an eye.
6. The method of claim 1 , wherein forming the patterned conductive layer comprises:
depositing a layer of photoresist on the polymer layer;
patterning the photoresist with a mask;
removing the patterned photoresist to expose the polymer layer;
depositing the conductive material on the exposed polymer layer; and
removing the remaining photoresist.
7. The method of claim 6 , wherein depositing the conductive material includes one of an e-beam evaporation process, a sputtering process or an electroplating process.
8. The method of claim 1 , further comprising:
depositing a layer of photoresist on a substrate; and
forming the first layer of polymer material on the photoresist.
9. The method of claim 8 , wherein the substrate comprises a material selected from the group consisting of silicon, glass, and quartz.
10. The method of claim 9 , further comprising removing the photoresist layer so as to separate the device from the substrate.
11. The method of claim 1 , wherein the cable region includes one or more conductive lines formed of the conductive material, said lines coupling the electrode array with one or more circuit elements in the power and data management region.
12. The method of claim 1 , wherein the circuit elements of the power and data management region include one of a chip or a circuit arrangement configured to provide control signals to the electrode array.
13. The method of claim 1 , wherein the exposed electrode array includes electrodes arranged in a pattern that mimics the density pattern of ganglion cells in a retina.
14. The method of claim 1 , wherein the exposed electrode array includes electrodes arranged in a pattern having an irregular density.
15. The method of claim 1 , wherein removing a portion of the second polymer layer comprises:
depositing a layer of photoresist on the second polymer layer;
patterning the photoresist with a mask;
removing the patterned photoresist to expose portions of the second polymer layer; and
etching the exposed portions of the second polymer layer.
16. A method of fabricating an integrated intraocular retinal prosthesis device having an electrode array region, a power and data management region and a cable region connecting the electrode region with the power and data management region, the method comprising:
forming a patterned layer of conductive material on a first layer of polymer material, said patterned conductive layer defining circuit elements of the power and data management region, the electrode region and the cable region, wherein the cable region includes one or more conductive lines formed of the conductive material, said lines coupling the electrode array with one or more circuit elements in the power and data management region;
covering the patterned conductive layer with a second polymer layer; and
removing a portion of the second polymer layer in the electrode array region so as to expose at least a portion of the patterned conductive layer to form an exposed electrode array.