Procedure for the preparation of radioisotopes
A procedure for the preparation of radioisotopes consisting of a first step of electrodepositing a metallic isotope target to be irradiated on a target-holder element, a second step of irradiating the target, a third step of dissolving the target and a fourth set of purifying the radioisotope from the initial metallic isotope and from other possible radioactive and metallic impurities; the electrodeposition step in turn consisting of a dissolution operation in which the isotope to be irradiated is dissolved in a solution of HNO 3 with concentration from 0.5 to 2.5 M, a pH buffering operation, and a recirculation operation, in which the solution obtained above is circulated at a rate from 0.5 to 3 within an electrolytic cell during the current output within the cell itself; the electrodeposition of the target to be irradiated occurs within the electrolytic cell during the recirculation operation.
1. A procedure for the preparation of radioisotopes comprising a first step of electrodepositing a metallic isotope target to be irradiated on a target-holder element, a second step of irradiating said target, a third step of dissolving said target and a fourth step of purifying the radioisotope from the initial metallic isotope and from other possible radioactive and metallic impurities; said procedure being characterised in that said electrodeposition step comprises a dissolution operation in which the isotope to be irradiated is dissolved in a solution of HNO 3 with concentration from 0.5 to 2.5 M, a pH buffering operation, and a recirculation operation, in which the solution obtained above is circulated at a rate of 0.5 to 3 ml/min within an electrolytic cell during the output of current within the cell itself; said isotope target to be irradiated being produced by electrodeposition in said electrolytic cell during said recirculation operation.
2. A procedure according to claim 1 , characterised in that in the dissolution operation, the concentration of HNO3 is from to 2 to 2.5 M.
3. A procedure according to claim 1 , characterised in that during the recirculation operation the solution is circulated at a rate from 1 to 2 ml/min.
4. A procedure according to claim 1 , characterised in that said pH buffering operation is an alkalisation operation adapted to take the pH to a value from 5 to 13.5.
5. A procedure according to claim 1 , characterised in that said current output during the recirculation operation has an intensity from 40 to 100 mA and a difference of potential from 2 to 3 V.
6. A procedure according to claim 1 , characterised in that the electrodissolution step comprising a further recirculation operation in which a solution of HCl with concentration from 4 to 6 is circulated at a rate from 3 to 5 ml/min within the electrolytic cell during the output of current reversed with respect to that output during the electrodeposition step.
7. A procedure according to claim 1 , characterised in that the metallic isotope to be irradiated is comprised in the group consisting of 60 Ni, 61 Ni, 64 Ni, 110 Cd.
8. A procedure according to claim 1 , characterised in that the purification step comprises an operation of elution in an ion-exchange column by means of a concentration gradient HCl solution.