Use of octenidine dihydrochloride in semisolid preparations
The invention relates to the use of octenidine dihydrochloride for manufacturing a semisolid pharmaceutical composition for the treatment of wounds, atopic dermatitides, infected eczemas, dermatomycoses, vaginal infections, acne, herpes and/or for controlling multidrug-resistant pathogens, where the composition comprises from 0.005 to 5% by weight octenidine dihydrochloride, and a corresponding composition.
1. A semisolid pharmaceutical composition for the treatment of wounds, atopic dermatitides, infected eczemas, dermatomycoses, vaginal infections, acne, herpes and/or for controlling multidrug-resistant pathogens, comprising:
octenidine dihydrochloride in an amount from 0.005 to 5% by weight;
propylene glycol;
hydroxyethylcellulose; and
water.
2. The composition according to claim 1 , wherein the amount of octenidine dihydrochloride is from 0.01 to 2% by weight.
3. The composition according to claim 1 , wherein the composition is in a form selected from the group consisting of a gel, an O/W cream, W/O cream, O/W/O cream, W/O/W cream, ambiphilic cream, ointment and a suppository.
4. The composition according to claim 3 , wherein the composition is a topical composition.
5. The composition according to claim 2 , wherein the amount of octenidine dihydrochloride is from 0.02 to 1% by weight.
6. The composition according to claim 5 , wherein the amount of octenidine dihydrochloride is from 0.03 to 0.8% by weight.
7. The composition according to claim 6 , wherein the amount of octenidine dihydrochloride is form 0.05 to 0.5% by weight.