Pancreatic cancer genes
The present invention provides the art with the DNA coding sequences of polynucleotides that are up-or-down-regulated in cancer and dysplasia. These polynucleotides and encoded proteins or polypeptides can be used in the diagnosis or identification of cancer and dysplasia. Inhibitors of the up-regulated polynucleotides and proteins can decrease the abnormality of cancer and dysplasia. Enhancing the expression of down-regulated polynucleotides or introducing down-regulated proteins to cells can decrease the growth and/or abnormal characteristics of cancer and dysplasia.
1. An antibody preparation which specifically binds to a polypeptide encoded by SEQ ID NO:12.
2. The antibody preparation of claim 1 , wherein said antibody is a monoclonal antibody.
3. The antibody preparation of claim 1 , wherein said antibody is a polyclonal antibody.
4. The antibody preparation of claim 1 , wherein said antibody is labeled.
5. The antibody preparation of claim 1 , wherein said antibody is a single chain antibody.
6. The antibody preparation of claim 5 , wherein said antibody is mono-specific.
7. The antibody preparation of claim 5 , wherein said antibody is bi-specific.
8. The antibody preparation of claim 5 , wherein said antibody is bivalent.
9. The antibody preparation of claim 5 , wherein said antibody is tetravalent.