IP Library Granted Patent US 7,910,139
Granted Patent B2
US 7,910,139 · App. 10/580,190 · Granted Mar 22, 2011

Compositions for the treatment of affections of the oral cavity and upper respiratory tract

Assignee: Indena S.p.A.
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Quick Facts
Patent No.
US 7,910,139
App. No.
10/580,190
Granted
Mar 22, 2011
Kind
B2
Abstract

Compositions for the treatment of the affections of the oral cavity and upper respiratory tract include anthocyanosides, procyanidins and phloroglucinols. The anthocyanosides are derived from Vaccinium myrtillus extract, the procyanidins are derived from a Vitus vinifera extract, a Camellia sinensis extract or from other edible plants containing procyanidins, and the phloroglucinols are derived from Hypericum spp., Myrtus spp. or Humulus lupulus extracts.

Claims (26)

1. A composition, for the treatment of an affection of the oral cavity and upper respiratory tract, comprising:

1-200 mg anthocyanosides;

1-200 mg procyanidins; and

1-200 mg phloroglucinols,

Wherein the anthocyanosides are derived from a Vaccinium myrtillus extract, the procyanidins are derived from a Vitis vinifera extract, a Camellia sinensis extract or from another edible plant containing the procyanidins, and the phloroglucinols are derived from Hypericum spp., Myrtus spp. or Humulus lupulus extracts.

2. The composition as claimed in claim 1 , wherein the phloroglucinols are derived from Hypericum perforatum or Myrtus communis extracts, or from Humulus lupulus fractions enriched in α and β acids.

3. The composition as claimed in claim 2 , wherein 20-80% of the phloroglucinols from the β acids of Humulus lupulus are colupulone, and the α acids contain 20-80% of humulone.

4. The composition as claimed in claim 3 , wherein 60% of the phloroglucinols from the β acids of Humulus lupulus are colupulone, and the α acids contain 60% of humulone.

5. The composition as claimed in claim 1 , wherein the Hypericum sp extract is a Hypericum perforatum extract with a phloroglucinol content ranging from 20-80%.

6. The composition as claimed in claim 5 , wherein the phloroglucinols content of the Hypericum perforatum extract is 60%.

7. The composition as claimed in claim 2 , wherein the Myrtus communis extract is prepared from leaves of Myrtus communis by extraction with carbon dioxide at a pressure ranging from 235 to 260 bars and a temperature ranging from 40-60° C.

8. The composition as claimed in claim 7 , wherein the Myrtus communis extract has a myrtucommulone content of 35%.

9. The composition as claimed in claim 1 , further containing at least one essential oil.

10. The composition as claimed in claim 9 , wherein the essential oil is mint oil.

11. A method for the treatment of an affection of the oral cavity and upper respiratory tract, said method comprises: administering to a patient in need thereof an effective amount of a medicament containing:

1-200 mg anthocyanosides;

1-200 mg procyanidins; and

1-200 mg phloroglucinols,

Wherein the anthocyanosides are derived from a Vaccinium myrtillus extract, the procyanidins are derived from a Vitis vinifera extract, a Camellia sinensis extract or from another edible plant containing the procyanidins, and the phloroglucinols are derived from Hypericum spp., Myrtus spp. or Humulus lupulus extracts.

12. The method as claimed in claim 11 , wherein the phloroglucinols are derived from Hypericum perforatum or Myrtus communis extracts, or from Humulus lupulus fractions enriched in α and β acids.

13. The method as claimed in claim 12 , wherein 20-80% of the phloroglucinols from the β acids of Humulus lupulus are colupulone, and the α acids contain 20-80% of humulone.

14. The method as claimed in claim 13 , wherein 60% of the phloroglucinols from the β acids of Humulus lupulus are colupulone, and the α acids contain 60% of humulone.

15. The method as claimed in claim 11 , wherein the Hypericum sp extract is a Hypericum perforatum extract with a phloroglucinol content ranging from 20-80%.

16. The method as claimed in claim 15 , wherein the phloroglucinols content of the Hypericum perforatum extract is 60%.

17. The method as claimed in claim 12 , wherein the Myrtus communis extract is prepared from leaves of Myrtus communis by extraction with carbon dioxide at a pressure ranging from 235 to 260 bars and a temperature ranging from 40-60° C.

18. The method as claimed in claim 12 , wherein the Myrtus communis extract has a myrtucommulone content of 35%.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 23, 2006
From: BOMBARDELLI, EZIO
To: INDENA S.P.A.
Reel/Frame 017937/0672 →
Priority Claims (1)
IT MI2003A2287 · Nov 24, 2003 · national
Continuity (1)
Related Publication 20070104661A1 · May 10, 2007