Quinazolines useful as modulators of ion channels
The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
1. A compound selected from the group consisting of:
2. A pharmaceutical composition comprising a compound according to claim 1 , and a pharmaceutically acceptable carrier.
3. A method for treating or lessening the severity of a disorder or condition selected from acute, chronic, neuropathic, or inflammatory pain, or severe pain said method comprising the step of administering to said patient an effective amount of a composition according to claim 2 .
4. The method according to claim 3 , wherein the condition or disorder is back pain, head pain, or neck pain.
5. The method according to claim 3 , wherein the condition or disorder is severe pain, acute pain, postsurgical pain, back pain, or cancer pain.