Probe with multiple arms and system for deep electrical neurostimulation comprising such a probe

1. A probe ( 1 , 1 ′) for deep electrical neurostimulation comprising:

a tubular body ( 10 ) of biocompatible material with a lateral wall ( 11 ) defining a lumen ( 12 ), said tubular body ( 10 ) being configured to be implanted, for at least a part of a length of the tubular body inside a patient's body for reaching a region to be stimulated;

a plurality of arms ( 32 ) each bearing at least one stimulation electrode ( 40 ) and being able to pass from a first position in which they are housed inside of said tubular body ( 11 ) to a second position in which they project radially from said lateral wall ( 11 ) and inversely; and

means ( 20 and 50 ) for making said arms ( 32 ) pass from said first position to said second position and inversely;

a base element ( 31 ) of tubular shape placed inside of the lumen ( 12 ) of said tubular body ( 10 );

wherein a plurality of said arms ( 32 ) are connected together by the base element ( 31 ), and further wherein said arms ( 32 ) and said base element ( 31 ) make up a single part ( 30 ) of strap shape, wound so as to adapt to the shape of the lumen ( 12 ) of said tubular body ( 10 ).

2. The probe ( 1 , 1 ′) of claim 1 , in which all the arms ( 32 ) projecting from said lateral wall ( 11 ) from a single axial position (Z 301 and Z 302 ) are connected together by the single tubular-shaped base element ( 31 ) placed inside the lumen of said tubular body ( 10 ).

3. The probe ( 1 , 1 ′) of claim 1 , in which said strap has a thickness between 10 and 100 μm.

4. The probe ( 1 , 1 ′) of claim 3 , wherein said strap has a thickness between 12 and 50 μm.

5. The probe ( 1 , 1 ′) of claim 1 , in which a plurality of said arms ( 32 ) project from said lateral wall ( 11 ) from a single axial position (Z 301 , Z 302 ).

6. The probe ( 1 ) of claim 2 further including a plurality of groups of arms ( 301 and 302 ), the arms ( 32 ) of each group ( 301 and 302 ) projecting from said lateral wall ( 11 ) from a single axial position (Z 301 and 302 ) and each of said groups ( 301 , 302 ) corresponding to a different axial position (Z 301 and Z 302 ).

7. The probe ( 1 , 1 ′) of claim 1 , in which said arms ( 32 ) are evenly distributed around the lateral wall ( 11 ) of said tubular body ( 10 ).

8. The probe ( 1 , 1 ′) of claim 1 , in which the arms ( 32 ) are housed at least in part in channels ( 14 ) extending in the lateral wall ( 11 ) of said tubular body ( 10 ).

9. The probe ( 1 , 1 ′) of claim 8 , in which the arms ( 32 ) extend in the lateral wall ( 11 ) of said tubular body ( 10 ) along an oblique direction relative to the axis.

10. The probe ( 1 , 1 ′) of claim 8 , in which the means for making said arms pass from said first to said second position include a spring ( 20 ) arranged so as to exert on said arms ( 32 ) a force directed parallel to the axis of said tubular body ( 11 ), so as to push them to the outside through said channels ( 14 ).

11. The probe ( 1 , 1 ′) of claim 10 , in which said arms ( 32 ) are flexible, and are arranged so as to pass from said first to said second position and inversely by translational movement.

12. The probe ( 1 ) of claim 10 , in which the means to make said arms pass from said second to said first position include a stem ( 50 ) which can be actuated in compression for exerting a force opposed to that of said spring ( 20 ) so as to make said arms return into said tubular body ( 11 ) through said channels ( 14 ).

13. The probe ( 1 ) of claim 12 , in which said stem is a stylus ( 50 ) which can be introduced in the lumen ( 12 ) of said tubular body ( 11 ) to make the tubular body rigid in order for insertion of the tubular body in a patient's body.

14. The probe ( 1 ′) of claim 10 , in which the means to make said arms pass from said second to said first position include a cable ( 52 ) which can be actuated in traction for exerting a force opposed to that of said spring ( 20 ) so as to make said arms return into said tubular body ( 11 ) through said channels ( 14 ).

15. The probe ( 1 , 1 ′) of claim 1 , in which said arms ( 32 ) are made of an electrically insulating material and each have at least one electrode ( 40 ) on a respective surface thereof.

16. The probe ( 1 , 1 ′) of claim 15 , in which said arms ( 32 ) are made, at least in part, from a biocompatible insulating material chosen from the group consisting of polyimides, and in particular polyisoindroquinazorindiones (PIQ) and the polyimide Pi2611, and the benzocyclobutenes (BCB).

17. The probe of claim 1 , wherein at least one of said arms also comprises at least a measurement electrode having a smaller surface than that of said stimulation electrodes.

18. The probe of claim 17 , wherein a plurality of measurement electrodes are disposed near to each stimulation electrode.

19. The probe ( 1 , 1 ′) of claim 1 , including electrically conducting elements ( 60 ) extending into the lumen or inside of the lateral wall of said tubular element and forming electrical contacts with the electrodes ( 40 ) carried by said arms.

20. The probe ( 1 , 1 ′) of claim 19 , in which said electrodes ( 40 ) are planar electrodes connected to said electrically conducting elements ( 60 ) by means of planar conducting tracks ( 41 ) formed on said arms ( 32 ).

21. The probe ( 1 , 1 ′) of claim 19 , in which said conducting elements ( 60 ) extend to an end referred to as posterior of said tubular body ( 10 ) and include means of connection ( 61 ) to an electrical pulse generator for deep electrical neurostimulation ( 80 ).

22. The probe ( 1 , 1 ′) of claim 1 , in which said tubular body ( 10 ) is made of a biocompatible material chosen from the group consisting of silicones, siloxanes, polyurethane and polyvinyl chloride.

23. The probe ( 1 , 1 ′) of claim 1 , in which said tubular body ( 10 ) has a substantially cylindrical shape with a diameter between 0.5 and 5 mm.

24. The probe ( 1 , 1 ′) of claim 23 , in which said tubular body ( 10 ) has a diameter between 0.5 and 2 mm.

25. The probe ( 1 , 1 ′) of claim 1 , including a number of arms ( 32 ) between 3 and 60.

26. The probe ( 1 , 1 ′) of claim 25 , wherein the number of arms ( 32 ) is between 4 and 40.

27. The probe ( 1 , 1 ′) of claim 1 , in which said arms ( 32 ) have a length between 0.2 and 3 mm.

28. The probe of claim 1 , wherein the tubular body ( 10 ) has a length between 15 cm and 40 cm.

29. A system for deep electrical neurostimulation comprising:

an electrical pulse generator for deep electrical neurostimulation ( 80 ); and

at least one probe ( 1 ) as claimed in claim 1 , whose stimulation electrodes are electrically connected to said electrical pulse generator ( 80 ).

30. The system of claim 29 wherein at least an arm of said probe comprises at least a measurement electrode having a smaller surface than that of said stimulation electrodes, said system further comprising a measurement instrument electrically connected to said measurement electrodes.

31. The probe ( 1 , 1 ′) of claim 27 , wherein said arms ( 32 ) have a length between 0.4 and 2 mm.