IP Library › Granted Patent US 7,972,137
Granted Patent B2
US 7,972,137 · App. 10/876,491 · Granted Jul 5, 2011

Anti-microbial dental formulations for the prevention and treatment of oral mucosal disease

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Quick Facts
Patent No.
US 7,972,137
App. No.
10/876,491
Granted
Jul 5, 2011
Kind
B2
Abstract

Compositions and methods are directed to antimicrobial compositions and articles that release ●NO from the composition and/or article in an amount effective to prevent gingival and other oral mucosal diseases.

Claims (10)

1. A method for the treatment of gingival disease resulting from exposure of microorganisms in a living being, comprising:

providing a flexible film having a composition that dissolves in the mouth of a patient and releases an amount of nitric oxide (●NO) effective to treat a microorganism promoted gingival disease;

producing a cavity in the gum of a patient;

plugging the cavity with an amount of the film; and

closing the cavity.

2. The method according to claim 1 , wherein the composition is a nitrosyl-containing organometallic ionic salt or a chelate.

3. The method of claim 1 , further comprising the step of activating the film with light.

4. The method of claim 1 wherein the composition comprises a nitrosyl-containing organometallic compound.

5. The method of claim 1 wherein the nitrosyl-containing organometallic compound comprises nitroprusside.

6. The method of claim 1 , further comprising removing the film from the cavity before closing the cavity.

Continuity (2)
Provisional Application 60483236 · Jun 30, 2003
Related Publication 20040265244A1 · Dec 30, 2004