Coating agent for drug releasing stent, preparation method thereof and drug releasing stent coated therewith
View Patent ↗Disclosed are a coating agent for drug releasing stents, a method for preparing the same and a drug releasing stent coated therewith. The coating agent for drug releasing stents comprises nanoparticles with a biologically active material entrapped therein, wherein the particles are formed of a polyethyleneimine (PEI)-deoxycholic acid (DOCA) polymer (PDo) in which 1˜8 moles of DOCA are grafted per mole of PEI.
1. A coating agent for drug releasing stents, comprising a mixture of polyurethane and nanoparticles of a polyethyleneimine(PEI)-deoxycholic acid (DOCA) polymer (PDo), wherein a biologically active material is entrapped in said nanoparticles and wherein said polyethyleneimine(PEI)-deoxycholic acid (DOCA) polymer (PDo) is formed from 1-8 moles of DOCA per mole of PEI.
2. The coating agent according to claim 1 , wherein the biologically active material is taxol.