Stable vitamin B6 derivative
A compound represented by the following general formula (I) or a salt thereof: wherein R 1 represents a glycosyl group, a phosphate group, or a cyclic phosphate group bound to R 2 ; R 2 represents —CH 2 OH, —CHO, —CH 2 NH 2 , —CH 2 -amino acid residue, or —CH 2 —OPO 2 H; and R 3 represents hydrogen atom, or —PO 3 H 2 , and a composition for cosmetics, medicaments, foodstuffs, and/or feeds containing the aforementioned compound or a salt thereof.
1. A compound represented by the following general formula (I) or a salt thereof:
wherein R 1 represents a cyclic phosphate group bound to R 2 ; R 2 represents —CH 2 OH, —CHO, —CH 2 NH 2 , —CH 2 -amino acid residue, or —CH 2 —OPO 2 H; and R 3 represents a hydrogen atom, or —PO 3 H 2 .
2. The compound or a salt thereof according to claim 1 , which is pyridoxine 3,4′-cyclic phosphate or a salt thereof.
3. A compound represented by the following general formula (IV) or a salt thereof:
wherein R 4 represents —CH 2 OH, —CHO, or —CH 2 NH 2 , or represents —CH 2 OH, —CHO, or —CH 2 NH 2 protected with a protective group; R 5 represents a hydrogen atom, a protective group of hydroxyl group, a phosphate group, or a protected phosphate group; and R 6 represents a cyclic phosphate group bound to R 4 which may have a protective group.
4. A composition for a cosmetic, a medicament, a foodstuff, and/or a feed comprising a compound represented by the following general formula (V) or a salt thereof:
wherein R 7 represents a cyclic phosphate group bound to R 8 ; R 8 represents —CH 2 OH, —CHO, —CH 2 NH 2 , —CH 2 -amino acid residue, or —CH 2 —OPO 2 H; and R 9 represents a hydrogen atom, or —PO 3 H 2 .
5. A method for stabilizing calcium pantothenate contained in a cosmetic, a medicament, a foodstuff, and/or a feed from thermal decomposition and decomposition initiated by U.V. light by adding a compound represented by the general formula (V) or a salt thereof mentioned in claim 4 to the cosmetic, the medicament, the foodstuff, and/or the feed.
6. A composition for a cosmetic, a medicament, foodstuff, and/or a feed containing a compound represented by the general formula (V) or a salt thereof mentioned in claim 4 and at least one kind of vitamin, wherein stability of the vitamin is improved.
7. A composition comprising (A) a compound represented by the general formula (V) according to claim 4 , and (B) one or more kinds of substances selected from the group consisting of a whitening agent, an antioxidant, an antiphlogistic, a circulation accelerator, a cell activation agent, and an ultraviolet absorber, which is used as a whitening agent, an anti-aging agent, and/or an agent for suppressing wrinkle formation by exposure to ultraviolet light.
8. A whitening agent containing (A) a compound represented by the general formula (V) mentioned in claim 4 , and (B) arbutin.