IP Library Granted Patent US 8,012,930
Granted Patent B2
US 8,012,930 · App. 12/046,402 · Granted Sep 6, 2011

Methods of treating pervasive development disorders

Assignee: Curemark, LLC
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Quick Facts
Patent No.
US 8,012,930
App. No.
12/046,402
Granted
Sep 6, 2011
Kind
B2
Abstract

A therapeutic method for treating an individual diagnosed with PDD pervasive developmental disorder comprises determining the efficacy of digestive enzyme administration for the treatment of the individual based on a measure of the individual's chymotrypsin level, and administering digestive enzymes to the individual based on the determination of the measure of the individual's chymotrypsin level. A method for reducing the amount of methylphenidate (Ritalin) being taken by an individual with attention deficit disorder (ADD) or attention deficit hyperactivity disorder (ADHD) by administering a therapeutic amount of digestive enzymes is also provided.

Claims (14)

1. A method for treating an individual with Attention Deficit Disorder (ADD) or Attention Deficit Hyperactivity disorder (ADHD) who is taking methylphenidate, the method comprising the steps of:

measuring a level of chymotrypsin in a stool sample of the individual;

administering digestive enzymes comprising proteases, lipases and amylases to the individual in an amount effective to promote protein digestion to improve a symptom of the disorder if the level of chymotrypsin in the stool sample indicates that the person suffers from a deficiency in protein digestion;

monitoring a behavior of the individual; and

adjusting the amount of methylphenidate being taken by the individual to an appropriate therapeutic level based on improvement in the behavior of the individual.

2. The method of claim 1 , wherein the proteases comprise chymotrypsin.

3. The method of claim 1 , wherein the amount of methylphenidate being taken by the individual is decreased based on improvement in the behavior of the individual.

4. The method of claim 1 , wherein the digestive enzymes comprise 2-5 mg of chymotrypsin per dose or 60-100 mg of trypsin per dose.

5. The method of claim 1 , wherein the digestive enzymes comprise from 4,000 to 20,000 USP lipases per dose; proteases; and from 10,000-60,000 USP amylases per dose.

6. The method of claim 5 , wherein the proteases comprise from 10,000 to 50,000 USP per dose.

7. The method of claim 6 , wherein the proteases further comprise 2-5 mg of chymotrypsin per dose or 60-100 mg of trypsin per dose.

8. The method of claim 1 , wherein the individual's fecal chymotrypsin level is below 8.4 U/gm.

9. The method of claim 1 , wherein the individual's fecal chymotrypsin level is below 8.4 U/gm but above or equal to 4.2 U/gm.

10. The method of claim 1 , wherein the individual's fecal chymotrypsin level is below 4.2 U/gm.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 1, 2009
From: FALLON, JOAN M.
To: CUREMARK, LLC
Reel/Frame 022626/0948 →
Continuity (5)
Division 11213255 · Oct 18, 2005
Division 10681018 · Oct 8, 2003
Continuation 09707395 · Nov 7, 2000
Continuation In Part 09466559 · Dec 17, 1999
Related Publication 20080219966A1 · Sep 11, 2008