IP Library Granted Patent US 8,012,958
Granted Patent B2
US 8,012,958 · App. 11/910,967 · Granted Sep 6, 2011

Methods for treating anxiety related disorders

Assignee: Hythlam, Inc.
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Quick Facts
Patent No.
US 8,012,958
App. No.
11/910,967
Granted
Sep 6, 2011
Kind
B2
Abstract

The present invention relates to methods of and compositions for treating and relieving symptoms and disease associated with indications caused by a physiological drive to alleviate a sensation of anxiety. In one treatment method, methods of, and compositions for, modulating the expression of certain GABAA receptor subunits are used to treat anxiety-related disorders and depressive disorders associated with physiological tolerance to endogenous neurosteroids.

Claims (5)

1. A method of treating an obsessive compulsive disorder in a patient comprising administering to the patient a composition comprising flumazenil in a pharmaceutically acceptable carrier, wherein the flumazenil is administered in a therapeutically effective quantity.

2. The method of claim 1 , wherein the therapeutically effective quantity of flumazenil is between 0.5 mg/day and 10 mg/day.

3. The method of claim 1 , wherein the flumazenil is administered at a rate of between 0.1 and 0.3 mg over predetermined time intervals for a total administration of between 0.5 mg/day and 10 mg/day.

4. The method of claim 3 , wherein the predetermined time interval is in the range of 1 and 15 minutes.

5. The method of claim 1 , wherein the flumazenil is administered at a rate of between 0.1 and 0.3 mg over predetermined time intervals for a total administration of between 1.0 mg/day and 3.0 mg/day.

Assignments (4)
SECURITY INTEREST Recorded Aug 15, 2022
From: ONTRAK, INC.(F.K.A. CATASYS, INC., F.K.A. HYTHIAM, INC.); LD ACQUISITION HOLDINGS, INC.; LIFEDOJO INC.
To: U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT
Reel/Frame 060806/0473 →
RELEASE OF SECURITY INTEREST Recorded Jul 29, 2022
From: GOLDMAN SACHS SPECIALTY LENDING GROUP, L.P., AS COLLATERAL AGENT
To: ONTRAK, INC. (FORMERLY KNOWN AS CATASYS, INC.)
Reel/Frame 060672/0554 →
SECURITY INTEREST Recorded Feb 10, 2020
From: HYTHIAM, INC (N/K/A CATASYS, INC.)
To: GOLDMAN SACHS SPECIALTY LENDING GROUP, L.P.
Reel/Frame 051767/0204 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 9, 2007
From: SABNANI, SANJAY; WESSON, DONALD
To: HYTHIAM, INC.
Reel/Frame 020091/0065 →
Continuity (4)
Provisional Application 60728979 · Oct 21, 2005
Provisional Application 60729013 · Oct 21, 2005
Provisional Application 60669033 · Apr 7, 2005
Related Publication 20080280885A1 · Nov 13, 2008