Patch containing nonsteroidal anti-inflammatory and analgesic agent
An adhesive patch containing a non-steroidal anti-inflammatory agent, comprising a support and an adhesive layer laminated on this support, wherein the adhesive layer contains a non-steroidal anti-inflammatory agent having a carboxyl group or its salt, and polyethylene glycol having an average molecular weight of 1000 or more.
1. A storage stable adhesive patch comprising:
a support; and
an adhesive layer laminated on the support, the adhesive layer comprising
1-25% by mass of sodium diclofenac,
1-6% by mass of polyethylene glycol having an average molecular weight in an amount selected from the group consisting of 1300-1600, 2600-3800 and 7300-9300,
1-6% by mass of zinc stearate,
ammonium chloride present in the range of 0.5-10 times the number of moles of sodium diclofenac,
20-45% by mass of alicyclic petroleum resin,
10-35% by mass of styrene-isoprene-styrene block copolymer, and
2-20% by mass of polyisobutylene.
2. The adhesive patch according to claim 1 , wherein the adhesive layer further comprises 0.1-5% by mass of L-menthol.
3. The adhesive patch according to claim 1 , wherein the adhesive layer further comprises 0.1-10% by mass of oleic acid.
4. The adhesive patch according to claim 1 , wherein the adhesive layer further comprises 0.1-5% by mass of L-menthol, and 0.1-10% by mass of oleic acid.
5. The adhesive patch according to claim 1 , wherein the adhesive layer further comprises
0.1-5% by mass of L-menthol,
0.1-10% by mass of oleic acid, and
10-50% by mass of a plasticizer.