Method and system for nerve stimulation and cardiac sensing prior to and during a medical procedure
A method of performing a medical procedure, such as surgery, is provided. A nerve is stimulated in order to adjust the beating of the heart to a first condition, such as a stopped or slowed condition. The medical procedure is performed on the heart or another organ. The stimulation of the nerve is stopped in order to adjust the beating of the heart to a second condition, such as a beating condition. The heart itself may also be stimulated to a beating condition, such as by pacing. The stimulation of the nerve may be continued in order to allow the medical procedure to be continued. A sensor to sense a characteristic of a fluid or tissue, such as an impending contraction, may be also used during the medical procedure. Systems and devices for performing the medical procedure are also provided.
1. A method of performing a cardiac medical procedure on a patient, comprising:
a) electrically stimulating a heart to adjust beating of the heart;
b) delivering a stent device to the stimulated heart while the heart is beating; and
c) reducing electrical stimulation of the heart to readjust beating of the heart after delivering the stent device.
2. The method of claim 1 , wherein the heart is stimulated by transvascular stimulation.
3. The method of claim 2 , wherein the transvascular stimulation comprises delivering a pacemaker lead through a catheter to the ventricle of the heart of the patient.
4. The method of claim 1 , wherein the stimulating of the heart comprises pacing the heart.
5. The method of claim 1 further comprising: administering at least one drug during the cardiac medical procedure.
6. The method of claim 5 , wherein the drug is selected from the group consisting of: a beta-blocker, a cholmergic agent, a cholinesterase inhibitor, a calcium channel blocker, a sodium channel blocker, a potassium channel agent, adenosine, an adenosine receptor agonist, an adenosine deaminase inhibitor, dipyridamole, a monoamine oxidase inhibitor, digoxin, digitalis, lignocaine, a bradykinin agent, a serotoninergic agonist, an antiarrythmic agent, a cardiac glycoside, a local anesthetic, atropine, a calcium solution, an agent that promotes heart rate, an agent that promotes heart contractions, dopamine, a catecholamine, an inotrope glucagon, a hormone, forskolin, epinephrine, norepinephrine, thyroid hormone, a phosphodiesterase inhibitor, prostacyclin, prostaglandin and a methylxanthine.
7. The method of claim 1 , wherein the stimulating of the heart comprises stimulating the Purkinje fibers.
8. The method of claim 1 , wherein the cardiac medical procedure is a heart valve replacement procedure.
9. The method of claim 8 , wherein the stent device is a replacement heart valve.
10. A method of performing a cardiac medical procedure, comprising:
a) obtaining a stent device;
b) electrically stimulating a heart to adjust beating of the heart to a first condition;
c) delivering the stent device to the stimulated heart when the beating of the stimulated heart has been adjusted to the first condition, when the heart is beating in the first condition; and
d) reducing electrical stimulation of the heart to adjust beating of the heart to a second condition after delivering the stent device.
11. The method of claim 10 further comprising: stimulating the heart a subsequent time in order to re-adjust beating of the heart to the first condition.
12. The method of claim 10 wherein stimulating the heart comprises transvascular stimulation.
13. The method of claim 10 wherein reducing stimulation of the heart comprises stopping stimulation of the heart to achieve the second condition.
14. The method of claim 10 , wherein the first condition is a slowed condition.
15. The method of claim 10 , wherein the second condition is a beating condition.
16. The method of claim 10 further comprising: stimulating the heart in order to adjust beating of the heart to the second condition.
17. The method of claim 10 , wherein stimulating comprises pacing the heart to achieve the first condition.
18. The method of claim 10 further comprising: administering at least one drug during the cardiac procedure.
19. The method of claim 18 wherein the drug is selected from the group consisting of: a beta-blocker, a cholmergic agent, a cholinesterase inhibitor, a calcium channel blocker, a sodium channel blocker, a potassium channel agent, adenosine, an adenosine receptor agonist, an adenosine deaminase inhibitor, dipyridamole, a monoamine oxidase inhibitor, digoxin, digitalis, lignocaine, a bradykinin agent, a serotoninergic agonist, an antiarrythmic agent, a cardiac glycoside, a local anesthetic, atropine, a calcium solution, an agent that promotes heart rate, an agent that promotes heart contractions, dopamine, a catecholamine, an inotrope glucagon, a hormone, forskolin, epinephrine, norepinephrine, thyroid hormone, a phosphodiesterase inhibitor, prostacyclin, prostaglandin and a methylxanthine.
20. The method of claim 10 , wherein the stimulating of the heart comprises stimulating the Purkinje fibers.
21. The method of claim 10 , wherein the stent device is a replacement heart valve.
22. A method of performing a cardiac medical procedure on a human patient, comprising:
a) obtaining a stent device;
b) delivering a pacemaker lead through a catheter to the ventricle of the heart of the patient;
c) electrically stimulating the heart;
d) delivering the stent device to the heart while the heart is beating; and
e) decreasing the electrical stimulation of the heart after delivering the stent device.
23. The method of claim 22 , wherein the stent device is a stent.
24. The method of claim 22 , wherein the stent device is a replacement heart valve.
25. The method of claim 22 , wherein stimulating the heart comprises pacing the heart.
26. The method of claim 22 , wherein the cardiac medical procedure comprises a heart valve replacement procedure.
27. The method of claim 22 , wherein stimulating the heart comprises stimulating the Purkinje fibers.
28. A method of performing a cardiac medical procedure on a patient, comprising:
a) delivering a pacemaker lead through a catheter to the ventricle of the heart of the patient;
b) electrically stimulating the heart to adjust beating of the heart to a first rate;
c) delivering a stent device to the heart when the heart is beating at the first rate;
d) reducing electrical stimulation of the heart to adjust beating of the heart to a second rate after delivering the stent device;
e) removing the pacemaker lead from the heart of the patient.