IP Library › Granted Patent US 8,076,315
Granted Patent B2
US 8,076,315 · App. 12/090,131 · Granted Dec 13, 2011

Pharmacological treatments for sleep disorders (apnoe) with prostanoid receptor antagonists

Assignee: The Board of Trustees of the University of Illinois
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,076,315
App. No.
12/090,131
Granted
Dec 13, 2011
Kind
B2
Abstract

This invention is directed to methods for preventing or ameliorating sleep-related breathing disorders. The method comprises administration to a patient in need thereof an effective dose of one or a combination of prostanoid receptor antagonists (eg. ramatroban, ifetroban, diphloretin, phosphate, polyphloretin phosphate, seratrodast, SC19220). The prostanoid receptor antagonist or combination of prostanoid receptor antagonists can be administered in conjunction with one or more serotonin receptor agonists, one or more cannabinoids receptor agonists, one or more serotonin reuptake inhibitors, one or more noradrenalin reuptake inhibitors, a combination of reuptake inhibitors, an inhibitor of prostanoid synthesis, or any combination of the foregoing.

Claims (1)

1. A method for ameliorating a sleep-related breathing disorder, the method comprising the step of administering an effective dose of one or more prostanoid receptor antagonists to a patient in need thereof, wherein said prostanoid receptor antagonist is selected from the group consisting of ramatroban, ifetroban, seratrodast, diphloretin phosphate, polyphloretin phosphate, or SC19220.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 13, 2008
From: CARLEY, DAVID W.; RADULOVACKI, MIODRAG
To: THE BOARD OF TRUSTEES OF THE UNIVERISTY OF ILLINOIS
Reel/Frame 020938/0046 →
Continuity (2)
Provisional Application 60726901 · Oct 14, 2005
Related Publication 20080261922A1 · Oct 23, 2008