IP Library › Granted Patent US 8,097,759
Granted Patent B2
US 8,097,759 · App. 12/830,018 · Granted Jan 17, 2012

Inflammatory cytokine release inhibitor

Assignee: Institute of Medicinal Molecular Design, Inc.
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Quick Facts
Patent No.
US 8,097,759
App. No.
12/830,018
Granted
Jan 17, 2012
Kind
B2
Abstract

A medicament having inhibitory activity against NF-κB activation, which comprises a compound represented by the following general formula (I) or a pharmacologically acceptable salt as an active ingredient: wherein X represents a connecting group, A represents hydrogen atom or acetyl group, E represents an aryl group or a heteroaryl group, and ring X represents an arene or a heteroarene.

Claims (3)

1. A compound represented by the following formula or a salt thereof:

2. A medicament comprising the compound according to claim 1 or a pharmacologically acceptable salt thereof, and at least one pharmacologically acceptable pharmaceutical additive.

3. An NF-κB inhibitor comprising the compound according to claim 1 or a salt thereof.

Priority Claims (1)
JP 2000-383202 · Dec 18, 2000 · national
Continuity (3)
Continuation 11835978 · Aug 8, 2007
Division 10433619
Related Publication 20100274051A1 · Oct 28, 2010