Granted Patent
B2
US 8,158,107 · App. 11/542,670 · Granted Apr 17, 2012
Genes and proteins associated with angiogenesis and uses thereof
Assignee:
National Jewish Health
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Abstract
Disclosed is a panel of biomarkers associated with angiogenesis, and the use of such biomarkers (genes, proteins, homologues and analogs thereof) to regulate angiogenesis. Methods for identifying compounds useful for regulating angiogenesis and conditions related thereto are disclosed.
Claims (2)
1. A method to promote angiogenesis in cells or a tissue of a patient that has, or is at risk of developing, a condition selected from stroke or ischemia, comprising contacting the cells or tissue from the patient with an effective amount of a MAGP-2 protein having the amino acid sequence of SEQ ID NO:43.
2. The method of claim 1 , wherein the MAGP-2 protein is encoded by a nucleic acid molecule comprising the nucleic acid sequence of SEQ ID NO:124.
Assignments (4)
CHANGE OF NAME
Recorded Jan 31, 2012
From: NATIONAL JEWISH MEDICAL AND RESEARCH CENTER
To: NATIONAL JEWISH HEALTH
Reel/Frame 027627/0791 →
CHANGE OF NAME
Recorded Jan 18, 2012
From: NATIONAL JEWISH MEDICAL AND RESEARCH CENTER
To: NATIONAL JEWISH HEATH
Reel/Frame 027556/0074 →
CONFIRMATORY LICENSE
Recorded Jun 25, 2008
From: NATIONAL JEWISH CTR FOR IMMNLGY/RESP M
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 021150/0268 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jan 2, 2007
From: SCHIEMANN, WILLIAM P.; ALBIG, ALLAN R.
To: NATIONAL JEWISH MEDICAL AND RESEARCH CENTER
Reel/Frame 018698/0731 →
Continuity (3)
Provisional Application
60772694
· Sep 30, 2005
Provisional Application
60816969
· Jun 27, 2006