IP Library › Granted Patent US 8,168,804
Granted Patent B2
US 8,168,804 · App. 12/165,369 · Granted May 1, 2012

Large stoke shift NIR dyes

Assignee: Vanderbilt University
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Quick Facts
Patent No.
US 8,168,804
App. No.
12/165,369
Granted
May 1, 2012
Kind
B2
Abstract

A compound of the following formula: wherein R 1 is SO 3 H; R 2 is chosen from carboxylic acid group and SO 3 H; and R 3 is chosen from Cl, carboxylic acid group, amino, amino-carboxylic acid group, amido group, amino-amido group, and methods of use related to imaging.

Claims (10)

1. A compound of the following formula:

wherein R 1 is SO 3 H; R 2 is chosen from carboxylic acid group and SO 3 H; and R 3 is chosen from:

an amino-succinimidyl ester group, or an amino-maleimide group

2. The compound of claim 1 , wherein R 1 and R 2 are SO 3 H.

3. The compound of claim 1 , wherein R 3 is:

4. The compound of claim 1 , wherein R 3 is:

5. The compound of claim 1 , wherein R 3 is

6. The compound of claim 1 , wherein R 3 is chosen from an amino-succinimidyl ester group and an amino-maleimide group.

7. A compound of claim 1 of the following formula:

8. A compound of claim 1 of the following formula:

Assignments (2)
EXECUTIVE ORDER 9424, CONFIRMATORY LICENSE Recorded Feb 20, 2009
From: VANDERBILT UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 022287/0718 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 25, 2008
From: PHAM, WELLINGTON; GORE, JOHN C.
To: VANDERBILT UNIVERSITY
Reel/Frame 021586/0001 →
Continuity (2)
Provisional Application 60947293 · Jun 29, 2007
Related Publication 20090029405A1 · Jan 29, 2009